ID   PLHD1_RAT               Reviewed;         505 AA.
AC   B1WBU8;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Pleckstrin homology domain-containing family D member 1;
DE            Short=PH domain-containing family D member 1;
GN   Name=Plekhd1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the PLEKHD1 family. {ECO:0000305}.
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DR   EMBL; BC161896; AAI61896.1; -; mRNA.
DR   RefSeq; NP_001121038.1; NM_001127566.1.
DR   AlphaFoldDB; B1WBU8; -.
DR   SMR; B1WBU8; -.
DR   PaxDb; B1WBU8; -.
DR   PRIDE; B1WBU8; -.
DR   Ensembl; ENSRNOT00000058301; ENSRNOP00000055103; ENSRNOG00000038297.
DR   GeneID; 500685; -.
DR   KEGG; rno:500685; -.
DR   UCSC; RGD:1566112; rat.
DR   CTD; 400224; -.
DR   RGD; 1566112; Plekhd1.
DR   eggNOG; ENOG502QTF5; Eukaryota.
DR   GeneTree; ENSGT00950000183017; -.
DR   HOGENOM; CLU_035364_0_0_1; -.
DR   InParanoid; B1WBU8; -.
DR   OMA; ANEDMGM; -.
DR   OrthoDB; 1334476at2759; -.
DR   PhylomeDB; B1WBU8; -.
DR   TreeFam; TF320494; -.
DR   PRO; PR:B1WBU8; -.
DR   Proteomes; UP000002494; Chromosome 6.
DR   Bgee; ENSRNOG00000038297; Expressed in ovary and 10 other tissues.
DR   Genevisible; B1WBU8; RN.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Methylation; Reference proteome.
FT   CHAIN           1..505
FT                   /note="Pleckstrin homology domain-containing family D
FT                   member 1"
FT                   /id="PRO_0000349197"
FT   DOMAIN          28..136
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          264..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          146..391
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        266..284
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         502
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:B2RPU2"
SQ   SEQUENCE   505 AA;  59055 MW;  FDBF9F471CACE753 CRC64;
     MFTSKSNSVS PSPSLEQADA DALDISTKVQ LYGVLWKRPF GRSSAKWSRR FFIIKESFLL
     YYSESERKSF ETNKYFNIHP KGVIPLGGCL VEAREEPSMP YAMKISHQDF HGNVLLAAES
     EFEQTQWLEM LQESGKVTWK NAQLGEAMIK SLEAQGLQLA KEKQEYLDKL MEETEELCLQ
     REQREELERL NQVLEAEKQQ FEEVVQELKV EQEQIKRELE LTARCLKGVE QEKKELRHLT
     ESLQHTLEEL SIEKKKTLEM LEEDKNQPQP LTNQSEQPPA TDGLHSNLRQ IEERMQELLA
     EKLLAEKRMK ENEERSRALE EEREFYSSQS QALQNSLQEL TAEKQQAEQE LKAEVKVRMD
     LERRLREAEA ALRSLEQGLN SKVRNKEKEE RMRADVSHLK RFFEECIRNA ELEAKMPVIM
     KNSVYIHKAA TRRIKSCRFH RRRSSTSWND MKPSQSFMTS QLEANNIEEL KEVAKRLSRD
     QRFRESIYHI MATQPGASAL PRGGK