ID   PLIA_BOTAS              Reviewed;          63 AA.
AC   P81077;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Myotoxin inhibitor protein {ECO:0000303|PubMed:9307037};
DE            Short=BaMIP {ECO:0000303|PubMed:9307037};
DE            Short=MIP;
DE   AltName: Full=Phospholipase A2 inhibitor;
DE            Short=alpha-PLI;
DE   Flags: Fragment;
OS   Bothrops asper (Terciopelo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Crotalinae; Bothrops.
OX   NCBI_TaxID=8722;
RN   [1]
RP   PROTEIN SEQUENCE, AND SUBCELLULAR LOCATION.
RC   TISSUE=Blood;
RX   PubMed=9307037; DOI=10.1042/bj3260853;
RA   Lizano S., Lomonte B., Fox J.W., Gutierrez J.M.;
RT   "Biochemical characterization and pharmacological properties of a
RT   phospholipase A2 myotoxin inhibitor from the plasma of the snake Bothrops
RT   asper.";
RL   Biochem. J. 326:853-859(1997).
CC   -!- FUNCTION: Binds to and neutralizes the activities of basic
CC       phospholipase A2 (PLA2) myotoxin isoforms.
CC   -!- SUBUNIT: Oligomer composed of five 23-25 kDa subunits (PubMed:9307037).
CC       Homotrimer; non-covalently linked (By similarity).
CC       {ECO:0000250|UniProtKB:A1XRN2, ECO:0000269|PubMed:9307037}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:9307037}.
CC       Note=Secreted in plasma. {ECO:0000269|PubMed:9307037}.
CC   -!- TISSUE SPECIFICITY: Expressed by the liver. {ECO:0000305}.
CC   -!- PTM: Contains 2 disulfide bonds. {ECO:0000250|UniProtKB:P21755}.
CC   -!- SIMILARITY: Belongs to the alpha-type phospholipase A2 inhibitor
CC       family. {ECO:0000305}.
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DR   AlphaFoldDB; P81077; -.
DR   SMR; P81077; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Lectin; Secreted.
FT   CHAIN           1..63
FT                   /note="Myotoxin inhibitor protein"
FT                   /id="PRO_0000046714"
FT   NON_TER         63
FT                   /evidence="ECO:0000305|PubMed:9307037"
SQ   SEQUENCE   63 AA;  7154 MW;  F1E6AF75D8489CE6 CRC64;
     DEVDPDGKVL NSLIDTLMHL QKEFANLKYA FLTVHKARSF GSGSERLYVT NKEIKNFEPL
     GDI