ID   PLMS_LAMNA              Reviewed;          13 AA.
AC   P83009;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Phospholemman-like protein;
DE   AltName: Full=PLMS;
DE   Flags: Fragment;
OS   Lamna nasus (Porbeagle shark) (Squalus nasus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Lamniformes; Alopiidae; Lamna.
OX   NCBI_TaxID=7849;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   TISSUE=Rectal gland {ECO:0000269|PubMed:11676495};
RX   PubMed=11676495; DOI=10.1006/bbrc.2001.5826;
RA   Schuurmans Stekhoven F.M.A.H., Flik G., Wendelaar Bonga S.E.;
RT   "N-terminal sequences of small ion channels in rectal glands of sharks: a
RT   biochemical hallmark for classification and phylogeny?";
RL   Biochem. Biophys. Res. Commun. 288:670-675(2001).
CC   -!- FUNCTION: Induces a hyperpolarization-activated chloride current when
CC       expressed in Xenopus oocytes. May have a functional role in muscle
CC       contraction. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Microsome membrane; Single-pass type I membrane
CC       protein. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type
CC       I membrane protein {ECO:0000305}.
CC   -!- PTM: Major plasma membrane substrate for camp-dependent protein kinase
CC       (PK-A) and protein kinase C (PK-C) in several different tissues.
CC       Phosphorylated in response to insulin and adrenergic stimulation (By
CC       similarity). {ECO:0000250|UniProtKB:P56513}.
CC   -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000250|UniProtKB:P56513}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chloride; Chloride channel; Direct protein sequencing;
KW   Endoplasmic reticulum; Ion channel; Ion transport; Membrane; Microsome;
KW   Phosphoprotein; Transmembrane; Transport.
FT   CHAIN           1..>13
FT                   /note="Phospholemman-like protein"
FT                   /id="PRO_0000148181"
FT   NON_TER         13
FT                   /evidence="ECO:0000303|PubMed:11676495"
SQ   SEQUENCE   13 AA;  1542 MW;  081373C69724A444 CRC64;
     VSDVPNNDDR FTY