ID   PLNKY_LACPN             Reviewed;          30 AA.
AC   C0HJC0;
DT   16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 1.
DT   25-MAY-2022, entry version 6.
DE   RecName: Full=Bacteriocin plantaricin KL-1Y {ECO:0000303|PubMed:25862353};
OS   Lactiplantibacillus plantarum (Lactobacillus plantarum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=1590 {ECO:0000303|PubMed:25862353};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, AND MASS
RP   SPECTROMETRY.
RC   STRAIN=KL-1 {ECO:0000303|PubMed:25862353};
RX   PubMed=25862353; DOI=10.1007/s11274-015-1851-0;
RA   Rumjuankiat K., Perez R.H., Pilasombut K., Keawsompong S., Zendo T.,
RA   Sonomoto K., Nitisinprasert S.;
RT   "Purification and characterization of a novel plantaricin, KL-1Y, from
RT   Lactobacillus plantarum KL-1.";
RL   World J. Microbiol. Biotechnol. 31:983-994(2015).
CC   -!- FUNCTION: Bacteriocin with activity against species of Lactobacillus,
CC       Lactococcus, Pediococcus, Leuconostoc and against B.subtilis and, to a
CC       lesser extent, against B.coagulans, B.cereus and species of
CC       Enterococcus, Listeria, Kocuria, Staphylococcus, Corynebacterium,
CC       Salmonella, Pseudomonas and Escherichia. {ECO:0000269|PubMed:25862353}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Activity is stable between pH 2 and 12 at 25 degrees Celsius.
CC         {ECO:0000269|PubMed:25862353};
CC       Temperature dependence:
CC         Thermostable in a pH-dependent manner. Retains 100% activity after 15
CC         minutes at 121 degrees Celsius at pH 4. Retained activity is lower
CC         when incubated at basic pH or pH 2. {ECO:0000269|PubMed:25862353};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25862353}.
CC   -!- MASS SPECTROMETRY: Mass=3498.16; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:25862353};
CC   -!- MISCELLANEOUS: Antimicrobial activity is lost upon treatment with
CC       alpha-chymotrypsin, trypsin, pepsin and actinase E, but not when
CC       treated with proteinase K or endoproteinase Glu-C.
CC       {ECO:0000269|PubMed:25862353}.
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DR   AlphaFoldDB; C0HJC0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Secreted.
FT   PEPTIDE         1..30
FT                   /note="Bacteriocin plantaricin KL-1Y"
FT                   /evidence="ECO:0000269|PubMed:25862353"
FT                   /id="PRO_0000433782"
SQ   SEQUENCE   30 AA;  3498 MW;  6441E10F949ACABB CRC64;
     GRADYNFGYG LGRGTRKFFN GIGRWVRKTF