ID   PLP1_BORPE              Reviewed;         258 AA.
AC   P40415; Q7VTH9;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Probable parvulin-type peptidyl-prolyl cis-trans isomerase;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Protein p13;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   OrderedLocusNames=BP3561;
OS   Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257313;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251;
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA   Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA   Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA   Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA   Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA   Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA   Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 168-258.
RC   STRAIN=BVK;
RA   von Kaenel B., Chung S., Parish R.W.;
RT   "Evidence for a virus encoded protein recognising rRNA gene upstream
RT   repeats in Dictyostelium discoideum.";
RL   Submitted (FEB-1993) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=7878732; DOI=10.1016/s0968-0004(00)88941-0;
RA   Rudd K.E., Sofia H.J., Koonin E.V., Plunkett G. III, Lazar S.,
RA   Rouviere P.E.;
RT   "Conserved sequence motifs in bacterial and bacteriophage chaperonins.";
RL   Trends Biochem. Sci. 20:14-15(1995).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
CC   -!- SIMILARITY: Belongs to the PpiC/parvulin rotamase family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Was originally (Ref.2) thought to originate from Dictyostelium
CC       discoideum. {ECO:0000305}.
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DR   EMBL; BX640421; CAE43820.1; -; Genomic_DNA.
DR   EMBL; X70280; CAB56780.1; -; mRNA.
DR   RefSeq; NP_882074.1; NC_002929.2.
DR   RefSeq; WP_003821314.1; NZ_CP039022.1.
DR   AlphaFoldDB; P40415; -.
DR   SMR; P40415; -.
DR   STRING; 257313.BP3561; -.
DR   GeneID; 45390042; -.
DR   KEGG; bpe:BP3561; -.
DR   PATRIC; fig|257313.5.peg.3854; -.
DR   eggNOG; COG0760; Bacteria.
DR   HOGENOM; CLU_034646_1_1_4; -.
DR   OMA; YEQAKPT; -.
DR   BRENDA; 5.2.1.8; 899.
DR   Proteomes; UP000002676; Chromosome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR000297; PPIase_PpiC.
DR   InterPro; IPR023058; PPIase_PpiC_CS.
DR   PROSITE; PS01096; PPIC_PPIASE_1; 1.
DR   PROSITE; PS50198; PPIC_PPIASE_2; 1.
PE   2: Evidence at transcript level;
KW   Isomerase; Reference proteome; Rotamase; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..258
FT                   /note="Probable parvulin-type peptidyl-prolyl cis-trans
FT                   isomerase"
FT                   /id="PRO_0000193444"
FT   DOMAIN          127..219
FT                   /note="PpiC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00278"
FT   CONFLICT        168..172
FT                   /note="PGSAE -> GDPRQ (in Ref. 2; CAB56780)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   258 AA;  28964 MW;  06EA409FC1B02D07 CRC64;
     MKRIAMLAAA CVIAVPAFAQ NVATVNGKPI TQKSLDEFVK LVVSQGATDS PQLREQIKQE
     MINRQVFVQA AEKDGVAKQA DVQTEIELAR QGILVRALMA DYLQKHPVTD AQVKAEYEKI
     KKEQAGKMEY KVRHILVEDE KTANDLLAQV KSNKNKFDDL AKKNSKDPGS AERGGDLGWA
     PATNYVQPFA EAVTKLKKGQ LVDKPVQTQF GWHVIQVDDT RPVEFPAMDQ VRPQLEEMLR
     QQTLANYQKQ LREQAKIQ