ID   PLP2_RABIT              Reviewed;         152 AA.
AC   Q95MN6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Proteolipid protein 2;
GN   Name=PLP2;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RX   PubMed=11472841; DOI=10.1016/s0925-4773(01)00424-5;
RA   Milde S., Viebahn C., Kirchner C.;
RT   "Proteolipid protein 2 mRNA is expressed in the rabbit embryo during
RT   gastrulation.";
RL   Mech. Dev. 106:129-132(2001).
CC   -!- FUNCTION: May play a role in cell differentiation in the intestinal
CC       epithelium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Maximally expressed at the beginning of
CC       gastrulation. {ECO:0000269|PubMed:11472841}.
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DR   EMBL; AF314164; AAK72225.1; -; mRNA.
DR   RefSeq; NP_001075566.1; NM_001082097.1.
DR   AlphaFoldDB; Q95MN6; -.
DR   GeneID; 100008797; -.
DR   KEGG; ocu:100008797; -.
DR   CTD; 5355; -.
DR   InParanoid; Q95MN6; -.
DR   OrthoDB; 1521294at2759; -.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008253; Marvel.
DR   Pfam; PF01284; MARVEL; 1.
DR   PROSITE; PS51225; MARVEL; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..152
FT                   /note="Proteolipid protein 2"
FT                   /id="PRO_0000156821"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          19..137
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT   CARBOHYD        108
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   152 AA;  16747 MW;  496450726686EC32 CRC64;
     MADSERLSAP GCWAACTTFS RTRKGILLLA EIILCLVILI CFSAGTSGYS SLSVVEMVLA
     IVFFVIYMCD LHTRAPFINW PWSDFFRTLI AAILYLITSI FVLVERGNHS KIAAGVLGLL
     ATCLFGYDAY FTFPLRQQRH TAAPTDPTDG PV