ID   PLP2_RAT                Reviewed;         151 AA.
AC   Q6P742;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Proteolipid protein 2;
GN   Name=Plp2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Prostate;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May play a role in cell differentiation in the intestinal
CC       epithelium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
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DR   EMBL; BC061844; AAH61844.1; -; mRNA.
DR   RefSeq; NP_997484.1; NM_207601.1.
DR   AlphaFoldDB; Q6P742; -.
DR   IntAct; Q6P742; 1.
DR   STRING; 10116.ENSRNOP00000039462; -.
DR   PaxDb; Q6P742; -.
DR   PRIDE; Q6P742; -.
DR   GeneID; 302562; -.
DR   KEGG; rno:302562; -.
DR   UCSC; RGD:1587363; rat.
DR   CTD; 5355; -.
DR   RGD; 1587363; Plp2.
DR   VEuPathDB; HostDB:ENSRNOG00000039496; -.
DR   eggNOG; KOG4788; Eukaryota.
DR   HOGENOM; CLU_108546_4_0_1; -.
DR   InParanoid; Q6P742; -.
DR   OMA; ICEMIFA; -.
DR   OrthoDB; 1521294at2759; -.
DR   PhylomeDB; Q6P742; -.
DR   TreeFam; TF317387; -.
DR   PRO; PR:Q6P742; -.
DR   Proteomes; UP000002494; Chromosome X.
DR   Bgee; ENSRNOG00000039496; Expressed in lung and 19 other tissues.
DR   Genevisible; Q6P742; RN.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISO:RGD.
DR   GO; GO:0019956; F:chemokine binding; ISO:RGD.
DR   InterPro; IPR008253; Marvel.
DR   Pfam; PF01284; MARVEL; 1.
DR   PROSITE; PS51225; MARVEL; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..151
FT                   /note="Proteolipid protein 2"
FT                   /id="PRO_0000156822"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          19..137
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
SQ   SEQUENCE   151 AA;  16557 MW;  696489C90C58FAE5 CRC64;
     MADSERLSAP GCWLACTSFS RTKKGILLFA EIILCLVILI CFSASTSAYS SLSVIEMIFA
     AVLFVFYMCD LHSKISFINW PWTDFFRSLI AAILYLITSI VVLVEGRGSS KIVAGVLGLL
     ATLLFGYDAY ITFPLKQQRH TAAPTDPTDG P