ID   PLP2_SHEEP              Reviewed;          76 AA.
AC   Q28597;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Proteolipid protein 2;
DE   AltName: Full=Differentiation-dependent protein A4;
DE   AltName: Full=Intestinal membrane A4 protein;
DE   Flags: Fragment;
GN   Name=PLP2; Synonyms=A4;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Conceptus membrane, and Uterus;
RX   PubMed=7510284; DOI=10.1016/s0021-9258(17)37276-9;
RA   Kramer K.K., Duffy J.Y., Klemann S.W., Bixby J.A., Low B.G., Pope W.F.,
RA   Roberts R.M.;
RT   "Selective cloning of cDNA for secretory proteins of early embryos.
RT   Identification of a transiently expressed Kunitz domain protein from
RT   preimplantation sheep trophoblast.";
RL   J. Biol. Chem. 269:7255-7261(1994).
CC   -!- FUNCTION: May play a role in cell differentiation in the intestinal
CC       epithelium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
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DR   EMBL; U01946; AAC04310.1; -; mRNA.
DR   AlphaFoldDB; Q28597; -.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           <1..76
FT                   /note="Proteolipid protein 2"
FT                   /id="PRO_0000156823"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          <1..60
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT   CARBOHYD        31
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   76 AA;  7928 MW;  298EE95DAE39C199 CRC64;
     ISGPWSDFFR ALGAVILYLM TSIVVLVERG NNSKGAAGVL GLCAAGLFGY DAYITFPSGT
     RRHTAAPTDP ADGPVR