ID   PLP3_ORYSI              Reviewed;         413 AA.
AC   B8B7E7;
DT   19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Patatin-like protein 3;
DE            EC=3.1.1.-;
GN   Name=PLP3; ORFNames=OsI_24874;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Possesses non-specific lipolytic acyl hydrolase (LAH)
CC       activity. Hydrolyzes phospholipids as well as galactolipids. May play a
CC       role in disease resistance (By similarity). {ECO:0000250}.
CC   -!- DOMAIN: The nitrogen atoms of the two glycine residues in the GGXR
CC       motif define the oxyanion hole, and stabilize the oxyanion that forms
CC       during the nucleophilic attack by the catalytic serine during substrate
CC       cleavage. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the patatin family. {ECO:0000305}.
CC   -!- CAUTION: Lacks the conserved Asp residue expected to act as the active
CC       site proton acceptor. {ECO:0000305}.
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DR   EMBL; CM000132; EEC81509.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8B7E7; -.
DR   SMR; B8B7E7; -.
DR   EnsemblPlants; BGIOSGA025139-TA; BGIOSGA025139-PA; BGIOSGA025139.
DR   Gramene; BGIOSGA025139-TA; BGIOSGA025139-PA; BGIOSGA025139.
DR   HOGENOM; CLU_000288_144_1_1; -.
DR   OMA; RACGGET; -.
DR   Proteomes; UP000007015; Chromosome 7.
DR   GO; GO:0016298; F:lipase activity; IEA:UniProt.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Lipid degradation; Lipid metabolism; Plant defense;
KW   Reference proteome.
FT   CHAIN           1..413
FT                   /note="Patatin-like protein 3"
FT                   /id="PRO_0000425827"
FT   DOMAIN          54..245
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   REGION          384..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           58..61
FT                   /note="GGXR"
FT   ACT_SITE        100
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   413 AA;  43029 MW;  493083E35F260D7E CRC64;
     MEAGQDDAAD RLTYEIFSIL ESKFLFGYGG GGGGETKSLQ CAPPVSRGNR VCVLSVDGGA
     RPEDGLLAAA ALVRLEAAVQ RRAGSKAARL ADFFDVAAGS GAGGVLAAML FARGPCGRPM
     YSADDALGFL LRRVRRRGWS SRAGGLLRRP AGAFHKVFGE LTLRDTVRPV LVPCYDLATR
     APFLFSRADA AQSPAYDFRL RDACAATCAP SGGGAAVEAS SVDGVTRITA VGSGVALGNP
     TAAAITHVLN NRREFPAAAG VDNLLVISIG TGEAAGSSSR HRARTPVIAR IAAEGASDMV
     DQAVAMAFGQ HRTSNYVRIQ GMGVARRRGG GVACGGETAE KAVWVAEAML QQRNVEAVMF
     QGRRLAGETN AEKVERFARE LIKEHGRRKQ HVPPAASGGG GGGLDCHVSK KQP