PLP9_ARATH
ID PLP9_ARATH Reviewed; 384 AA.
AC Q93ZQ3; Q9M1W9;
DT 19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Probable inactive patatin-like protein 9;
DE Short=AtPLP9;
DE AltName: Full=Patatin-related phospholipase A IIIdelta;
DE Short=pPLAIIId;
DE AltName: Full=Phospholipase A IIIB;
DE Short=AtPLAIIIB;
GN Name=PLP9; OrderedLocusNames=At3g63200; ORFNames=F16M2.50;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=21447788; DOI=10.1105/tpc.110.081240;
RA Li M., Bahn S.C., Guo L., Musgrave W., Berg H., Welti R., Wang X.;
RT "Patatin-related phospholipase pPLAIIIbeta-induced changes in lipid
RT metabolism alter cellulose content and cell elongation in Arabidopsis.";
RL Plant Cell 23:1107-1123(2011).
CC -!- TISSUE SPECIFICITY: Highly expressed in roots and at lower levels in
CC flowers and siliques. {ECO:0000269|PubMed:21447788}.
CC -!- SIMILARITY: Belongs to the patatin family. {ECO:0000305}.
CC -!- CAUTION: Lacks the conserved Ser residue involved in nucleophilic
CC attack and essential for hydrolase activity. Its enzyme activity is
CC therefore unsure. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB86421.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL138648; CAB86421.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE80447.1; -; Genomic_DNA.
DR EMBL; AY056391; AAL08247.1; -; mRNA.
DR EMBL; BT001015; AAN46769.1; -; mRNA.
DR PIR; T48109; T48109.
DR RefSeq; NP_567142.1; NM_116185.2.
DR AlphaFoldDB; Q93ZQ3; -.
DR SMR; Q93ZQ3; -.
DR BioGRID; 10809; 6.
DR IntAct; Q93ZQ3; 6.
DR STRING; 3702.AT3G63200.1; -.
DR PaxDb; Q93ZQ3; -.
DR PRIDE; Q93ZQ3; -.
DR ProteomicsDB; 234772; -.
DR EnsemblPlants; AT3G63200.1; AT3G63200.1; AT3G63200.
DR GeneID; 825495; -.
DR Gramene; AT3G63200.1; AT3G63200.1; AT3G63200.
DR KEGG; ath:AT3G63200; -.
DR Araport; AT3G63200; -.
DR TAIR; locus:2077269; AT3G63200.
DR eggNOG; KOG0513; Eukaryota.
DR HOGENOM; CLU_000288_144_1_1; -.
DR InParanoid; Q93ZQ3; -.
DR OMA; DSHAQIS; -.
DR OrthoDB; 1209603at2759; -.
DR PhylomeDB; Q93ZQ3; -.
DR BRENDA; 3.1.1.23; 399.
DR PRO; PR:Q93ZQ3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93ZQ3; baseline and differential.
DR Genevisible; Q93ZQ3; AT.
DR GO; GO:0016298; F:lipase activity; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; SSF52151; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome.
FT CHAIN 1..384
FT /note="Probable inactive patatin-like protein 9"
FT /id="PRO_0000425821"
FT DOMAIN 33..234
FT /note="PNPLA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT REGION 363..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 37..42
FT /note="GXGXXG"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT MOTIF 221..223
FT /note="DGA/G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT ACT_SITE 221
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
SQ SEQUENCE 384 AA; 41487 MW; B96BFABF67776900 CRC64;
MEMDLSKVTL DIFTKLEQKW LSHCDSSRKT RILSIDGGGT TGIVAAASIL HLEHQIRLQT
GDPHAHISDF FDIVAGTGIG GILAALLVAD DGSGRPMFTA RDAVKFVAEK NSELFEIRYT
GVFRRNKRYS GKSMERVLET AFRREDGKVL TMKDTCKPLL VPCYDLKTSA PFVFSRAGAS
ESPSFDFELW KVCRATSATP SLFKPFSVVS VDGKTSCSAV DGGLVMNNPT AAAVTHVLHN
KRDFPSVNGV DDLLVLSLGN GPSTMSSSPG RKLRRNGDYS TSSVVDIVVD GVSDTVDQML
GNAFCWNRTD YVRIQANGLT SGGAEELLKE RGVETAPFGV KRILTESNGE RIEGFVQRLV
ASGKSSLPPS PCKESAVNPL ADGR
