ID   PLPA_MYCGA              Reviewed;         854 AA.
AC   Q7NBF9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 2.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Fibronectin-binding protein PlpA;
DE   AltName: Full=Pneumoniae-like protein A;
GN   Name=plpA; OrderedLocusNames=MYCGA3200; ORFNames=MGA_1199;
OS   Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS   (Mycoplasmoides gallisepticum).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=710127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R(low / passage 15 / clone 2);
RX   PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA   Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA   Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT   "The complete genome sequence of the avian pathogen Mycoplasma
RT   gallisepticum strain R(low).";
RL   Microbiology 149:2307-2316(2003).
RN   [2]
RP   PROTEIN SEQUENCE OF 487-494, AND FIBRONECTIN-BINDING.
RC   STRAIN=R(high / passage 164), and R(low / passage 14);
RX   PubMed=16495551; DOI=10.1128/iai.74.3.1777-1785.2006;
RA   May M., Papazisi L., Gorton T.S., Geary S.J.;
RT   "Identification of fibronectin-binding proteins in Mycoplasma gallisepticum
RT   strain R.";
RL   Infect. Immun. 74:1777-1785(2006).
CC   -!- FUNCTION: Binds immobilized fibronectin, specifically the
CC       gelatin/heparin-binding domain.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC       Note=Epitopes are exposed at the cell surface. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Absent in high passage extracts (passage 164) versus low
CC       passage (passage 14) due to a 17 bp duplication that adds a premature
CC       codon. {ECO:0000269|PubMed:16495551}.
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DR   EMBL; AE015450; AAP56670.2; -; Genomic_DNA.
DR   RefSeq; WP_011113562.1; NC_004829.2.
DR   AlphaFoldDB; Q7NBF9; -.
DR   SMR; Q7NBF9; -.
DR   KEGG; mga:MGA_1199; -.
DR   PATRIC; fig|233150.7.peg.356; -.
DR   HOGENOM; CLU_333116_0_0_14; -.
DR   OrthoDB; 2105660at2; -.
DR   Proteomes; UP000001418; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Cell membrane; Coiled coil; Direct protein sequencing; Membrane;
KW   Reference proteome; Repeat; Virulence.
FT   CHAIN           1..854
FT                   /note="Fibronectin-binding protein PlpA"
FT                   /id="PRO_0000380124"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..109
FT                   /note="Fibronectin-binding"
FT   REGION          247..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..434
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          743..766
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          835..854
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          384..622
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..269
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..428
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        748..766
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         689..854
FT                   /note="Missing (in high passage 164 isolate)"
SQ   SEQUENCE   854 AA;  98693 MW;  12C652231F789CBB CRC64;
     MDNNQNNFNQ PGQQGFDQYQ QQSGALVSYG YDANGNPVSD PSLAVYDANG MLINQNQYDQ
     NQQQEYDQYG NPVGMLSGNV YSQENDPYYQ QYNQQQNQGY EQQYDEYGNP IGLLPGSENQ
     QNNQQQYDQY GNPIGMLPGG TNDQAYDPNQ MQYDQYGNPV GMLAGVNAND QGYDYNQMQY
     DEYGNPVGML PGGNANDQGY DYNQMQYDEY GNPPALYDNN QQDYYGYDQN QQYDQANNQL
     AVVDENYEQE QQVESNEEPA HEQDLREFLN NNSDTELVSY YEEEEDEKKP RNKKKQRQTA
     QARGLLPELA TVNQPDQTPI TPHLEAPVHY DENEELSTDD LSDDINLDQN QAVHHDAEDD
     VINIPIEDIE SALLPKFEEI QRHNLEEIQK VKLEAAENFK VLQRANEELK SSNNELKTTN
     QQLKTSNEAL EDSNKRIESQ LQALLDSIND IKSKNNQPSQ EEVDSRSKLE QRLEELAYKL
     DQTKEIIDET SESSRESFQQ SKDQLIENFE KKIELLTEKL NQTQESFNQS QEAKQQQDKE
     FAQKIERIIE QTKEANDSLQ NRVKESSLDM ESKLENKFES FADKLTEITS KKISEKMTEQ
     QASKKEEIDS LQSSFQKALS EVVSKVENYA NQSQLQSQHL NQTLSYHQQQ INNSLRQSAQ
     MAQMAQMQHM MPQQMLMGMN NPYGFNHHTM MPPVHQYQQL PPPPPVQAPA QQLLPTINNP
     LQLPNENPTL FEKLMLANMF KQTINPPQPQ PQALPQPHPQ PQQLPPQILA LPPTVVQQPN
     YLVPQPPRQP DYYSNRLNER MMLDDAYNAG YDEAVYELEN QYYPPAYEYP EYEEIQPSFR
     RRGGRAKFDP YNNR