ID   PLPHP_CORGL             Reviewed;         221 AA.
AC   O24748;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2002, sequence version 2.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Pyridoxal phosphate homeostasis protein {ECO:0000255|HAMAP-Rule:MF_02087};
DE            Short=PLP homeostasis protein {ECO:0000255|HAMAP-Rule:MF_02087};
GN   OrderedLocusNames=Cgl2153, cg2364;
OS   Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS   JCM 1318 / LMG 3730 / NCIMB 10025).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196627;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9240446; DOI=10.1006/bbrc.1997.6930;
RA   Kobayashi M., Asai Y., Hatakeyama K., Kijima N., Wachi M., Nagai K.,
RA   Yukawa H.;
RT   "Cloning, sequencing, and characterization of the ftsZ gene from coryneform
RT   bacteria.";
RL   Biochem. Biophys. Res. Commun. 236:383-388(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA   Ikeda M., Nakagawa S.;
RT   "The Corynebacterium glutamicum genome: features and impacts on
RT   biotechnological processes.";
RL   Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA   Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA   Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA   Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA   Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT   impact on the production of L-aspartate-derived amino acids and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- FUNCTION: Pyridoxal 5'-phosphate (PLP)-binding protein, which is
CC       involved in PLP homeostasis. {ECO:0000255|HAMAP-Rule:MF_02087}.
CC   -!- SIMILARITY: Belongs to the pyridoxal phosphate-binding protein
CC       YggS/PROSC family. {ECO:0000255|HAMAP-Rule:MF_02087}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAF20493.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB003132; BAA21689.1; -; Genomic_DNA.
DR   EMBL; BA000036; BAB99546.1; -; Genomic_DNA.
DR   EMBL; BX927154; CAF20493.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_601355.1; NC_003450.3.
DR   AlphaFoldDB; O24748; -.
DR   SMR; O24748; -.
DR   STRING; 196627.cg2364; -.
DR   KEGG; cgb:cg2364; -.
DR   KEGG; cgl:Cgl2153; -.
DR   PATRIC; fig|196627.13.peg.2091; -.
DR   eggNOG; COG0325; Bacteria.
DR   HOGENOM; CLU_059988_0_0_11; -.
DR   OMA; IEWHMIG; -.
DR   Proteomes; UP000000582; Chromosome.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.10; -; 1.
DR   HAMAP; MF_02087; PLP_homeostasis; 1.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   InterPro; IPR011078; PyrdxlP_homeostasis.
DR   PANTHER; PTHR10146; PTHR10146; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PIRSF; PIRSF004848; YBL036c_PLPDEIII; 1.
DR   SUPFAM; SSF51419; SSF51419; 1.
DR   TIGRFAMs; TIGR00044; TIGR00044; 1.
DR   PROSITE; PS01211; UPF0001; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate; Reference proteome.
FT   CHAIN           1..221
FT                   /note="Pyridoxal phosphate homeostasis protein"
FT                   /id="PRO_0000163194"
FT   MOD_RES         26
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02087"
FT   CONFLICT        39
FT                   /note="F -> L (in Ref. 1; BAA21689)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        82
FT                   /note="A -> S (in Ref. 1; BAA21689)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        106
FT                   /note="D -> E (in Ref. 1; BAA21689)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        164
FT                   /note="G -> D (in Ref. 1; BAA21689)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   221 AA;  23975 MW;  D97FEB437CC947FD CRC64;
     MQARIDATLN EHNRPEGSVR LLPVTKFHPV EDIKILQEFG VTAVGENREQ EARAKALELP
     DMDFHMIGQI QSKKANSIAR WAAAVHSVDS EKIAEALGRG VALALDRGDR TSDELPCFIQ
     LSLDGDPSRG GTPLSQVTQL ADCISDTTHL RFEGLMCVPP LGWGPEKAFS QARDVLSGLE
     EHFDRSLEFS AGMSGDLVAA IKHGSTIVRV GTEILGNRPL A