ID   PLPHP_VIBCH             Reviewed;         236 AA.
AC   Q9KUQ4;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Pyridoxal phosphate homeostasis protein {ECO:0000255|HAMAP-Rule:MF_02087};
DE            Short=PLP homeostasis protein {ECO:0000255|HAMAP-Rule:MF_02087};
GN   OrderedLocusNames=VC_0461;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Pyridoxal 5'-phosphate (PLP)-binding protein, which is
CC       involved in PLP homeostasis. {ECO:0000255|HAMAP-Rule:MF_02087}.
CC   -!- SIMILARITY: Belongs to the pyridoxal phosphate-binding protein
CC       YggS/PROSC family. {ECO:0000255|HAMAP-Rule:MF_02087}.
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DR   EMBL; AE003852; AAF93634.1; -; Genomic_DNA.
DR   PIR; E82321; E82321.
DR   RefSeq; NP_230115.1; NC_002505.1.
DR   RefSeq; WP_001256653.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KUQ4; -.
DR   SMR; Q9KUQ4; -.
DR   STRING; 243277.VC_0461; -.
DR   DNASU; 2615123; -.
DR   EnsemblBacteria; AAF93634; AAF93634; VC_0461.
DR   KEGG; vch:VC_0461; -.
DR   PATRIC; fig|243277.26.peg.434; -.
DR   eggNOG; COG0325; Bacteria.
DR   HOGENOM; CLU_059988_0_1_6; -.
DR   OMA; IEWHMIG; -.
DR   BioCyc; VCHO:VC0461-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IBA:GO_Central.
DR   Gene3D; 3.20.20.10; -; 1.
DR   HAMAP; MF_02087; PLP_homeostasis; 1.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   InterPro; IPR011078; PyrdxlP_homeostasis.
DR   PANTHER; PTHR10146; PTHR10146; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PIRSF; PIRSF004848; YBL036c_PLPDEIII; 1.
DR   SUPFAM; SSF51419; SSF51419; 1.
DR   TIGRFAMs; TIGR00044; TIGR00044; 1.
DR   PROSITE; PS01211; UPF0001; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate; Reference proteome.
FT   CHAIN           1..236
FT                   /note="Pyridoxal phosphate homeostasis protein"
FT                   /id="PRO_0000163209"
FT   MOD_RES         36
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02087"
SQ   SEQUENCE   236 AA;  26420 MW;  4707D84756371C14 CRC64;
     MRSIQQNIEH ITAQIESAQQ KCGRARSSVQ LLAVSKTKPV EAILEATQAG QRYFGENYVQ
     EGVDKIRYFA EHHPQLALEW HFIGPLQSNK TRLVAEHFDW VHTIDREKIA LRLSEQRPVN
     MPPLQVLIQV NTSGEASKSG IEPQQLFTLA ELISRLPNLT LRGLMSIPEN VPDYPAQLAA
     FTQLAELQQQ LAQKYPQIDT LSMGMSGDMQ AAIEAGSTIV RIGTAIFGER DYSRNA