ID   PLPL_MAGOY              Reviewed;         787 AA.
AC   P0CT18; L7IMP3;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2013, sequence version 1.
DT   03-AUG-2022, entry version 19.
DE   RecName: Full=Patatin-like phospholipase domain-containing protein OOU_Y34scaffold00095g16.3;
DE            EC=3.1.1.-;
GN   ORFNames=OOU_Y34scaffold00095g16.3;
OS   Magnaporthe oryzae (strain Y34) (Rice blast fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=1143189;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y34;
RX   PubMed=22876203; DOI=10.1371/journal.pgen.1002869;
RA   Xue M., Yang J., Li Z., Hu S., Yao N., Dean R.A., Zhao W., Shen M.,
RA   Zhang H., Li C., Liu L., Cao L., Xu X., Xing Y., Hsiang T., Zhang Z.,
RA   Xu J.-R., Peng Y.-L.;
RT   "Comparative analysis of the genomes of two field isolates of the rice
RT   blast fungus Magnaporthe oryzae.";
RL   PLoS Genet. 8:E1002869-E1002869(2012).
CC   -!- FUNCTION: Probable lipid hydrolase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PLPL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ELQ44171.1; Type=Erroneous gene model prediction; Note=The predicted gene OOU_Y34scaffold00095g16 has been split into 3 genes: OOU_Y34scaffold00095g16.1, OOU_Y34scaffold00095g16.2 and OOU_Y34scaffold00095g16.3.; Evidence={ECO:0000305};
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DR   EMBL; JH793327; ELQ44171.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; P0CT18; -.
DR   Proteomes; UP000011086; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Lipid degradation; Lipid metabolism; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..787
FT                   /note="Patatin-like phospholipase domain-containing protein
FT                   OOU_Y34scaffold00095g16.3"
FT                   /id="PRO_0000423551"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          375..566
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   REGION          47..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          745..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           406..410
FT                   /note="GXSXG"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   COMPBIAS        144..160
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        408
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   ACT_SITE        553
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
SQ   SEQUENCE   787 AA;  88461 MW;  DAD66CE20AB01316 CRC64;
     MTEKQINVPA RAYGFPPDAY DPSLLPDFDV SFLRPEDLEA FIQALSAPDT TQPPDDGLAS
     PRSPSARSFS SFDFTKRASS VLPDDAQVVA AHAAAAGGET APIPGDNDTN NANGFGNSSS
     QSLFITAQSD WAPVHEKVVG SQTHRQKKSS RRRKRSKAVA PGRRTRDETR EGYLYGLLKW
     PFLLIVGAWI VGLAVTYLFT RAYIFIYEQF VAWRGRREKL RRNMRATSRY PDWVKAARDL
     DNFLGNEAWK EQNEFAYYDS KTVRRVWDSL RRSRIRAAQM EASGSQSSSS SNEGKTTPIE
     DLKVLIEACV KNNFVGVENP RLYSQTYYGT KNLVQNYVDE VEKSLTALLE TKQLSMEDKR
     SIFKRVSANY GRTALCLSGG ASFAYYHFGV VKALLEEDLL PDVITGTSGG ALVAALVATR
     TNEELKKLLV PSLSTKITAC REPITVWFRR WWSTGARFDS VDWAKQCSWW SHGSMTFREA
     YERTGRILNV SCVPADPHSP TILCNYLTSP DCVIWSAVLA SAAVPGILNP VVLMMKKADG
     NLAPYSFGHK WKDGSLRTDI PIRALNLQFN VNFTIVSQVN PHINLFFFSS RGSVGQPVTH
     RRGRGWRGGF LGSATEQYIK LDLTKWLKVL RQLELLPRPL GQDWSQLWLQ QSFGGTVTIW
     PKTILSDFVH ILSDPDNARL ARMIHEGQQS TFPKIKFISN RLRIERLIER GRRETRPYIR
     RGSVESIISE DDLRELLLLR GSTNGTDEEI TTNDEMEFAS DEKAVLTEDE GQFDGVTDNT
     EGSPLLK