ID   PLP_RICCN               Reviewed;         282 AA.
AC   Q92H91;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Parvulin-like PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Peptidyl-prolyl cis-trans isomerase plp;
DE   AltName: Full=Rotamase plp;
DE   Flags: Precursor;
GN   Name=plp; OrderedLocusNames=RC0880;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PpiC/parvulin rotamase family.
CC       {ECO:0000305}.
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DR   EMBL; AE006914; AAL03418.1; -; Genomic_DNA.
DR   PIR; H97809; H97809.
DR   RefSeq; WP_010977485.1; NC_003103.1.
DR   AlphaFoldDB; Q92H91; -.
DR   SMR; Q92H91; -.
DR   EnsemblBacteria; AAL03418; AAL03418; RC0880.
DR   KEGG; rco:RC0880; -.
DR   HOGENOM; CLU_034646_1_3_5; -.
DR   OMA; YEQAKPT; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR000297; PPIase_PpiC.
DR   PROSITE; PS50198; PPIC_PPIASE_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Isomerase; Membrane; Rotamase; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..282
FT                   /note="Parvulin-like PPIase"
FT                   /id="PRO_0000289285"
FT   DOMAIN          138..231
FT                   /note="PpiC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00278"
SQ   SEQUENCE   282 AA;  31418 MW;  98CA02AF5865D535 CRC64;
     MKKLSVIFLS VSMLSGIAFA DKDKVVATYK GGEVKESQIM KEFKPQLNLQ SGETIKNFDD
     FPPQDQEKLI KIYVNNLLLK EEVAKSNITS SKEFQEKLEN AKNQLAQQEL LANYIKSNIT
     DKMFDDEYNK YVGNLKGKEQ IKVAHILVKS QKEANDIKTK LSKGGNFTKL AEELSLDKAS
     ASNGGVIGYI LLNQPGQLVP EFEKKAFALK VNEVSTPVKT DFGWHIIKVL EKKPVPIPTK
     EEAKVTIDNI LAAEVLKKYI ADLEAKANLK IMLPKADSKA GS