ID   PLS1_PHYPT              Reviewed;          19 AA.
AC   P86710;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Phylloseptin-P1 {ECO:0000303|Ref.1};
DE            Short=PLS-P1 {ECO:0000305};
OS   Phyllomedusa palliata (Jaguar leaf frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Phyllomedusinae;
OC   Phyllomedusa.
OX   NCBI_TaxID=44376;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS
RP   SPECTROMETRY, AND AMIDATION AT PHE-19.
RC   TISSUE=Skin secretion {ECO:0000269|Ref.1};
RA   Cardozo-Filho J.L., Monteiro J.R.N., Bloch C. Jr., Silva L.P.,
RA   Stabeli R.G., Calderon L.A.;
RT   "Identification of peptides from Amazonian Phyllomedusa palliata skin
RT   secretion by MALDI TOF/TOF.";
RL   Submitted (JUL-2010) to UniProtKB.
CC   -!- FUNCTION: Has antimicrobial activity. {ECO:0000250|UniProtKB:P85882}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands. {ECO:0000269|Ref.1}.
CC   -!- MASS SPECTROMETRY: Mass=2048.25; Mass_error=0.01; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Phylloseptin subfamily. {ECO:0000255}.
CC   -!- WEB RESOURCE: Name=The antimicrobial peptide database;
CC       URL="https://wangapd3.com/database/query_output.php?ID=00762";
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DR   AlphaFoldDB; P86710; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Antimicrobial;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..19
FT                   /note="Phylloseptin-P1"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000398812"
FT   MOD_RES         19
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   19 AA;  2049 MW;  F4A1C707AE708FD1 CRC64;
     FLSLIPHAIN AVSAIAKHF