PLS1_PHYTS
ID PLS1_PHYTS Reviewed; 19 AA.
AC P84929;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 9.
DE RecName: Full=Phylloseptin-1 {ECO:0000303|Ref.1};
DE Short=PStar 01 {ECO:0000303|Ref.1};
OS Phyllomedusa tarsius (Brownbelly leaf frog) (Phyllomedusa tarsia).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Phyllomedusinae;
OC Phyllomedusa.
OX NCBI_TaxID=306084;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS
RP SPECTROMETRY, AND AMIDATION AT LEU-19.
RC TISSUE=Skin secretion {ECO:0000269|Ref.1};
RA Prates M.V., Jardim D.P., Silva L.P., Gordo M., Leite J.R.S.A.,
RA Figueredo R.C.R., Amaral A.C., Felipe M.S.S., Bloch C. Jr.;
RT "Dermaseptins and phylloseptins from Phyllomedusa tarsius (Amphibia).";
RL Submitted (AUG-2006) to UniProtKB.
CC -!- FUNCTION: Has antimicrobial activity. {ECO:0000250|UniProtKB:P84566}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC -!- TISSUE SPECIFICITY: Expressed by the skin glands. {ECO:0000269|Ref.1}.
CC -!- MASS SPECTROMETRY: Mass=1953.23; Mass_error=0.1; Method=MALDI;
CC Evidence={ECO:0000269|Ref.1};
CC -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC Phylloseptin subfamily. {ECO:0000255}.
CC -!- WEB RESOURCE: Name=The antimicrobial peptide database;
CC URL="https://wangapd3.com/database/query_output.php?ID=02989";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; P84929; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Amphibian defense peptide; Antimicrobial;
KW Direct protein sequencing; Secreted.
FT PEPTIDE 1..19
FT /note="Phylloseptin-1"
FT /evidence="ECO:0000269|Ref.1"
FT /id="PRO_0000376045"
FT MOD_RES 19
FT /note="Leucine amide"
FT /evidence="ECO:0000269|Ref.1"
SQ SEQUENCE 19 AA; 1954 MW; 3ED1003A92D7F7A3 CRC64;
FLSLIPKIAG GIASLVKNL