ID   PLSLP_LOTGI             Reviewed;         121 AA.
AC   B3A0Q9;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Perlustrin-like protein;
DE   Flags: Precursor;
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND IDENTIFICATION.
RC   TISSUE=Mantle {ECO:0000269|Ref.1};
RA   Richardson P., Lucas S., Rokhsar D., Wang M., Lindquist E.A.;
RT   "DOE Joint Genome Institute Lottia gigantea EST project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PROTEIN SEQUENCE OF 36-98, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23145877; DOI=10.1111/febs.12062;
RA   Marie B., Jackson D.J., Ramos-Silva P., Zanella-Cleon I., Guichard N.,
RA   Marin F.;
RT   "The shell-forming proteome of Lottia gigantea reveals both deep
RT   conservations and lineage-specific novelties.";
RL   FEBS J. 280:214-232(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23145877}.
CC   -!- TISSUE SPECIFICITY: Component of the acid-insoluble organic matrix of
CC       calcified layers of the shell (at protein level).
CC       {ECO:0000269|PubMed:23145877}.
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DR   EMBL; FC630769; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_009050636.1; XM_009052388.1.
DR   AlphaFoldDB; B3A0Q9; -.
DR   EnsemblMetazoa; LotgiT238970; LotgiP238970; LotgiG238970.
DR   GeneID; 20250909; -.
DR   KEGG; lgi:LOTGIDRAFT_238970; -.
DR   CTD; 20250909; -.
DR   HOGENOM; CLU_2040710_0_0_1; -.
DR   OrthoDB; 979270at2759; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR000867; IGFBP-like.
DR   InterPro; IPR017891; Insulin_GF-bd_Cys-rich_CS.
DR   SUPFAM; SSF57184; SSF57184; 1.
DR   PROSITE; PS00222; IGFBP_N_1; 1.
DR   PROSITE; PS51323; IGFBP_N_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..121
FT                   /note="Perlustrin-like protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000415259"
FT   DOMAIN          24..104
FT                   /note="IGFBP N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00653"
FT   CARBOHYD        68
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        81
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        117
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   121 AA;  13822 MW;  0AED7454C6119438 CRC64;
     MKFGVGFLLS CLVALNTVQN MLALSCLPCD FDTLKCSPLP DDDDCFPAYT PCGCCPQCAG
     EEDDFCDNFT VRCHPDLVCV NATGFEKKFV YWYEFDFKGT CQESELETEY EYEYEENETK
     K