PLST1_ARATH
ID PLST1_ARATH Reviewed; 524 AA.
AC Q0WVE9; Q5XF02; Q9ZVN7;
DT 14-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Probable plastidic glucose transporter 1;
GN OrderedLocusNames=At1g05030; ORFNames=T7A14.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: May be involved in the efflux of glucose towards the cytosol.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q0WVE9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q0WVE9-2; Sequence=VSP_021554, VSP_021555;
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC98002.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005322; AAC98002.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27781.1; -; Genomic_DNA.
DR EMBL; BT015814; AAU94377.1; -; mRNA.
DR EMBL; BT020194; AAV59260.1; -; mRNA.
DR EMBL; AK226802; BAE98899.1; -; mRNA.
DR PIR; C86184; C86184.
DR RefSeq; NP_171996.2; NM_100382.3. [Q0WVE9-1]
DR AlphaFoldDB; Q0WVE9; -.
DR SMR; Q0WVE9; -.
DR STRING; 3702.AT1G05030.1; -.
DR iPTMnet; Q0WVE9; -.
DR PaxDb; Q0WVE9; -.
DR PRIDE; Q0WVE9; -.
DR ProteomicsDB; 234730; -. [Q0WVE9-1]
DR EnsemblPlants; AT1G05030.1; AT1G05030.1; AT1G05030. [Q0WVE9-1]
DR GeneID; 839340; -.
DR Gramene; AT1G05030.1; AT1G05030.1; AT1G05030. [Q0WVE9-1]
DR KEGG; ath:AT1G05030; -.
DR Araport; AT1G05030; -.
DR TAIR; locus:2205548; AT1G05030.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q0WVE9; -.
DR OrthoDB; 326501at2759; -.
DR PhylomeDB; Q0WVE9; -.
DR PRO; PR:Q0WVE9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q0WVE9; baseline and differential.
DR Genevisible; Q0WVE9; AT.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015149; F:hexose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015749; P:monosaccharide transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR045263; GLUT.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23503; PTHR23503; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chloroplast; Membrane; Plastid; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..524
FT /note="Probable plastidic glucose transporter 1"
FT /id="PRO_0000259885"
FT TRANSMEM 88..108
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..199
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 357..377
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 420..440
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 483..503
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT VAR_SEQ 320..339
FT /note="VAFIGGSLFVLQQFAGINGV -> GHVKLHSLGAPFLSYSNSRA (in
FT isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_021554"
FT VAR_SEQ 340..524
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_021555"
SQ SEQUENCE 524 AA; 57203 MW; 8330783B717E5F5E CRC64;
MWVTNTVLLY RPNSMNRLTF SYPTRLAHSR KASSFSRFFR SSKRKKRVTT LSTKKPDDDH
EISPVPPEKF SADLGWLSAF PHVSVASMAN FLFGYHIGVM NGPIVSIARE LGFEGNSILE
GLVVSIFIAG AFIGSIVAGP LVDKFGYRRT FQIFTIPLIL GALVSAQAHS LDEILCGRFL
VGLGIGVNTV LVPIYISEVA PTKYRGSLGT LCQIGTCLGI IFSLLLGIPA EDDPHWWRTM
LYVASMPGFL LALGMQFAVE SPRWLCKVGR LDDAKVVIRN IWGGSEVEKA VEDFQSVMKN
SGSNLNSRWL ELLDKPHSRV AFIGGSLFVL QQFAGINGVL YFSSLTFQNV GITSGAQASL
YVGVTNFAGA LCASYLIDKQ GRKKLLIGSY LGMAVSMFLI VYAVGFPLDE DLSQSLSILG
TLMYIFSFAI GAGPVTGLII PELSSNRTRG KIMGFSFSVH WVSNFLVGLF FLDLVEKYGV
GTVYASFGSV SLLAAAFSHL FTVETKGRSL EEIELSLNSR DDLS
