PLST2_ARATH
ID PLST2_ARATH Reviewed; 493 AA.
AC Q9FYG3;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Probable plastidic glucose transporter 2;
GN OrderedLocusNames=At1g67300; ORFNames=F1N21.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: May be involved in the efflux of glucose towards the cytosol.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FYG3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; AC002130; AAG00251.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34625.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58312.1; -; Genomic_DNA.
DR EMBL; AK226899; BAE98976.1; -; mRNA.
DR PIR; F96696; F96696.
DR RefSeq; NP_001320757.1; NM_001334287.1. [Q9FYG3-1]
DR RefSeq; NP_176898.1; NM_105398.4. [Q9FYG3-1]
DR AlphaFoldDB; Q9FYG3; -.
DR SMR; Q9FYG3; -.
DR STRING; 3702.AT1G67300.2; -.
DR PaxDb; Q9FYG3; -.
DR ProteomicsDB; 235070; -. [Q9FYG3-1]
DR EnsemblPlants; AT1G67300.1; AT1G67300.1; AT1G67300. [Q9FYG3-1]
DR EnsemblPlants; AT1G67300.3; AT1G67300.3; AT1G67300. [Q9FYG3-1]
DR GeneID; 843050; -.
DR Gramene; AT1G67300.1; AT1G67300.1; AT1G67300. [Q9FYG3-1]
DR Gramene; AT1G67300.3; AT1G67300.3; AT1G67300. [Q9FYG3-1]
DR KEGG; ath:AT1G67300; -.
DR Araport; AT1G67300; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q9FYG3; -.
DR OMA; GCIWLPE; -.
DR PhylomeDB; Q9FYG3; -.
DR PRO; PR:Q9FYG3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FYG3; baseline and differential.
DR Genevisible; Q9FYG3; AT.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015149; F:hexose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015749; P:monosaccharide transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR045263; GLUT.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23503; PTHR23503; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chloroplast; Membrane; Plastid; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..493
FT /note="Probable plastidic glucose transporter 2"
FT /id="PRO_0000259886"
FT TRANSMEM 52..72
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 293..313
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..376
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 424..444
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 450..470
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 53127 MW; E73FF9B86DAE5B06 CRC64;
MLGLQRETSS MYKRTSSRDY SPMIDVEDSS GLLENDVDNE METTNPSWKC SLPHVLVATI
SSFLFGYHLG VVNEPLESIS SDLGFSGDTL AEGLVVSVCL GGAFLGSLFS GGVADGFGRR
RAFQICALPM ILGAFVSGVS NSLAVMLLGR FLVGTGMGLG PPVAALYVTE VSPAFVRGTY
GSFIQIATCL GLMAALFIGI PVHNITGWWR VCFWLSTIPA ALLALGMFLC AESPQWLFKQ
GKIAEAEAEF ERLLGGSHVK TAMAELYKLD LDKTDEPDVV SLSELLYGRH SRVVFIGSTL
FALQQLSGIN AVFYFSSTVF KSAGVPSDLG NIFVGVSNLL GSVIAMVLMD KVGRKLLLLW
SFIGMAAAMA LQVGATSSYL PHFSALCLSV GGTLVFVLTF ALGAGPVPGL LLPEIFPSRI
RAKAMAFCMS VHWVINFFVG LLFLRLLEKL GPRLLYSMFS TFCLMAVMFV KRNVIETKGK
TLQEIEISLL AKP
