PLST3_ARATH
ID PLST3_ARATH Reviewed; 495 AA.
AC Q2V4B9; Q7X7U4; Q8RXX6; Q9CA87; Q9M9Z8;
DT 14-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 2.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=Probable plastidic glucose transporter 3;
GN OrderedLocusNames=At1g79820; ORFNames=F19K16.22, F20B17.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: May be involved in the efflux of glucose towards the cytosol.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=1;
CC IsoId=Q2V4B9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q2V4B9-2; Sequence=VSP_021556;
CC Name=3;
CC IsoId=Q2V4B9-3; Sequence=VSP_021557;
CC Name=4;
CC IsoId=Q2V4B9-4; Sequence=VSP_021558;
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF68114.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG52251.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC010793; AAF68114.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC011717; AAG52251.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE36303.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36304.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36305.1; -; Genomic_DNA.
DR EMBL; AY080624; AAL85970.1; -; mRNA.
DR EMBL; BT008550; AAP40377.1; -; mRNA.
DR EMBL; BT008693; AAP40499.1; -; mRNA.
DR PIR; B96829; B96829.
DR RefSeq; NP_001031303.1; NM_001036226.2. [Q2V4B9-3]
DR RefSeq; NP_178100.3; NM_106631.5. [Q2V4B9-1]
DR RefSeq; NP_850983.1; NM_180652.3. [Q2V4B9-1]
DR AlphaFoldDB; Q2V4B9; -.
DR SMR; Q2V4B9; -.
DR STRING; 3702.AT1G79820.2; -.
DR iPTMnet; Q2V4B9; -.
DR PaxDb; Q2V4B9; -.
DR PRIDE; Q2V4B9; -.
DR EnsemblPlants; AT1G79820.1; AT1G79820.1; AT1G79820. [Q2V4B9-1]
DR EnsemblPlants; AT1G79820.2; AT1G79820.2; AT1G79820. [Q2V4B9-1]
DR EnsemblPlants; AT1G79820.3; AT1G79820.3; AT1G79820. [Q2V4B9-3]
DR GeneID; 844321; -.
DR Gramene; AT1G79820.1; AT1G79820.1; AT1G79820. [Q2V4B9-1]
DR Gramene; AT1G79820.2; AT1G79820.2; AT1G79820. [Q2V4B9-1]
DR Gramene; AT1G79820.3; AT1G79820.3; AT1G79820. [Q2V4B9-3]
DR KEGG; ath:AT1G79820; -.
DR Araport; AT1G79820; -.
DR TAIR; locus:2017899; AT1G79820.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q2V4B9; -.
DR OMA; GFYNETW; -.
DR PhylomeDB; Q2V4B9; -.
DR PRO; PR:Q2V4B9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q2V4B9; baseline and differential.
DR Genevisible; Q2V4B9; AT.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005768; C:endosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR GO; GO:0015149; F:hexose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015749; P:monosaccharide transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR045263; GLUT.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23503; PTHR23503; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 2.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chloroplast; Membrane; Plastid; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..495
FT /note="Probable plastidic glucose transporter 3"
FT /id="PRO_0000259887"
FT TRANSMEM 55..75
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 294..314
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 330..350
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 357..377
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 384..404
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 425..445
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 451..471
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..132
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_021556"
FT VAR_SEQ 294..495
FT /note="VVFIGSTLFALQQLSGINAVFYFSSTVFKKAGVPSASANICVGVCNLLGSTV
FT AVVLMDKLGRKVLLIGSFAGMAVSLGLQAIAYTSLPSPFGTLFLSVGGMLLFVLSFATG
FT AGPVPSLLLSEICPGRLRATALAVCLAVHWVINFFVGLLFLRMLEQLGSVLLNAIFGFF
FT CVVAVIFVQKNVVETKGKSLQEIEISLLSSTQ -> VVWDKCCVLFLINCLQESWCTFS
FT LCKHMCRSLQPLRINCCCGFDG (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_021558"
FT VAR_SEQ 294..341
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_021557"
SQ SEQUENCE 495 AA; 52441 MW; 88ED7EF1DC45FA4A CRC64;
MDSVRRTYTI MRGRHIDKRV PSKEFLSALD KAETAVRLPT GTGKDCGNPS WKRSLPHVLV
ASLTSLLFGY HLGVVNETLE SISIDLGFSG NTIAEGLVVS TCLGGAFIGS LFSGLVADGV
GRRRAFQLSA LPMIVGASVS ASTESLMGML LGRFLVGIGM GIGPSVTALY VTEVSPAYVR
GTYGSSTQIA TCIGLLGSLF AGIPAKDNLG WWRICFWIST VPAAMLAVFM ELCVESPQWL
FKRGRAAEAE AVFEKLLGGS YVKAAMAELV KSDRGDDADS AKLSELLFGR SFRVVFIGST
LFALQQLSGI NAVFYFSSTV FKKAGVPSAS ANICVGVCNL LGSTVAVVLM DKLGRKVLLI
GSFAGMAVSL GLQAIAYTSL PSPFGTLFLS VGGMLLFVLS FATGAGPVPS LLLSEICPGR
LRATALAVCL AVHWVINFFV GLLFLRMLEQ LGSVLLNAIF GFFCVVAVIF VQKNVVETKG
KSLQEIEISL LSSTQ
