PLST4_ARATH
ID PLST4_ARATH Reviewed; 546 AA.
AC Q56ZZ7; Q93Z41; Q9LF13; Q9LLD8;
DT 14-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Plastidic glucose transporter 4;
DE Short=AtpGlcT;
GN OrderedLocusNames=At5g16150; ORFNames=T21H19.70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 34-546, FUNCTION, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=10810150; DOI=10.2307/3871001;
RA Weber A., Servaites J.C., Geiger D.R., Kofler H., Hille D., Groener F.,
RA Hebbeker U., Fluegge U.-I.;
RT "Identification, purification, and molecular cloning of a putative
RT plastidic glucose translocator.";
RL Plant Cell 12:787-802(2000).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 451-546.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: May be involved in the efflux of glucose towards the cytosol.
CC {ECO:0000269|PubMed:10810150}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000305|PubMed:10810150}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:10810150}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF74569.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD94093.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAC01856.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL391148; CAC01856.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92253.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92254.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92255.1; -; Genomic_DNA.
DR EMBL; AY058152; AAL25568.1; -; mRNA.
DR EMBL; AY091052; AAM13873.1; -; mRNA.
DR EMBL; AY117359; AAM51434.1; -; mRNA.
DR EMBL; AF215855; AAF74569.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK220813; BAD94093.1; ALT_INIT; mRNA.
DR PIR; T51485; T51485.
DR RefSeq; NP_568328.1; NM_121620.2.
DR RefSeq; NP_850828.1; NM_180497.2.
DR RefSeq; NP_974787.1; NM_203058.3.
DR AlphaFoldDB; Q56ZZ7; -.
DR SMR; Q56ZZ7; -.
DR BioGRID; 16748; 34.
DR IntAct; Q56ZZ7; 8.
DR STRING; 3702.AT5G16150.3; -.
DR TCDB; 2.A.1.1.102; the major facilitator superfamily (mfs).
DR iPTMnet; Q56ZZ7; -.
DR PaxDb; Q56ZZ7; -.
DR PRIDE; Q56ZZ7; -.
DR ProteomicsDB; 235071; -.
DR EnsemblPlants; AT5G16150.1; AT5G16150.1; AT5G16150.
DR EnsemblPlants; AT5G16150.2; AT5G16150.2; AT5G16150.
DR EnsemblPlants; AT5G16150.3; AT5G16150.3; AT5G16150.
DR GeneID; 831472; -.
DR Gramene; AT5G16150.1; AT5G16150.1; AT5G16150.
DR Gramene; AT5G16150.2; AT5G16150.2; AT5G16150.
DR Gramene; AT5G16150.3; AT5G16150.3; AT5G16150.
DR KEGG; ath:AT5G16150; -.
DR Araport; AT5G16150; -.
DR TAIR; locus:2181422; AT5G16150.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q56ZZ7; -.
DR OMA; PQCIPMN; -.
DR OrthoDB; 326501at2759; -.
DR PhylomeDB; Q56ZZ7; -.
DR BioCyc; ARA:AT5G16150-MON; -.
DR BioCyc; MetaCyc:AT5G16150-MON; -.
DR PRO; PR:Q56ZZ7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q56ZZ7; baseline and differential.
DR Genevisible; Q56ZZ7; AT.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..546
FT /note="Plastidic glucose transporter 4"
FT /id="PRO_0000259888"
FT TRANSMEM 105..125
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 240..260
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 345..365
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 410..430
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 441..461
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 477..497
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 503..523
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT CONFLICT 86
FT /note="Missing (in Ref. 4; AAF74569)"
FT /evidence="ECO:0000305"
FT CONFLICT 393
FT /note="F -> A (in Ref. 4; AAF74569)"
FT /evidence="ECO:0000305"
FT CONFLICT 419..420
FT /note="AL -> VH (in Ref. 4; AAF74569)"
FT /evidence="ECO:0000305"
FT CONFLICT 543..546
FT /note="TSGA -> FVSS (in Ref. 4; AAF74569)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 546 AA; 56970 MW; C2C7557976584450 CRC64;
MQSSTYAVKG NAAFAFQRRT FSSDRSTTST GIRFAGYKSL ATTGPLYCSG SEAMGATLAR
ADNGIQSVMS FSSVKARSVR AQASSDGDEE EAIPLRSEGK SSGTVLPFVG VACLGAILFG
YHLGVVNGAL EYLAKDLGIA ENTVLQGWIV SSLLAGATVG SFTGGALADK FGRTRTFQLD
AIPLAIGAFL CATAQSVQTM IVGRLLAGIG IGISSAIVPL YISEISPTEI RGALGSVNQL
FICIGILAAL IAGLPLAANP LWWRTMFGVA VIPSVLLAIG MAFSPESPRW LVQQGKVSEA
EKAIKTLYGK ERVVELVRDL SASGQGSSEP EAGWFDLFSS RYWKVVSVGA ALFLFQQLAG
INAVVYYSTS VFRSAGIQSD VAASALVGAS NVFGTAVASS LMDKMGRKSL LLTSFGGMAL
SMLLLSLSFT WKALAAYSGT LAVVGTVLYV LSFSLGAGPV PALLLPEIFA SRIRAKAVAL
SLGMHWISNF VIGLYFLSVV TKFGISSVYL GFAGVCVLAV LYIAGNVVET KGRSLEEIEL
ALTSGA
