ID   PLST_CARAU              Reviewed;         453 AA.
AC   P31393;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Plasticin;
OS   Carassius auratus (Goldfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Carassius.
OX   NCBI_TaxID=7957;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Retina;
RX   PubMed=1379821; DOI=10.1016/0896-6273(92)90175-d;
RA   Glasgow E., Druger R.K., Levine E.M., Fuchs C., Schechter N.;
RT   "Plasticin, a novel type III neurofilament protein from goldfish retina:
RT   increased expression during optic nerve regeneration.";
RL   Neuron 9:373-381(1992).
CC   -!- FUNCTION: Type III neurofilament.
CC   -!- TISSUE SPECIFICITY: Optic nerve.
CC   -!- DEVELOPMENTAL STAGE: Increased expression during optic nerve
CC       regeneration.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01188}.
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DR   EMBL; M90532; AAA49187.1; -; mRNA.
DR   PIR; JH0696; JH0696.
DR   AlphaFoldDB; P31393; -.
DR   SMR; P31393; -.
DR   Proteomes; UP000515129; Genome assembly.
DR   GO; GO:0045098; C:type III intermediate filament; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR006821; Intermed_filament_DNA-bd.
DR   InterPro; IPR002957; Keratin_I.
DR   InterPro; IPR027700; PRPH/Plasticin.
DR   PANTHER; PTHR45652:SF14; PTHR45652:SF14; 1.
DR   Pfam; PF00038; Filament; 1.
DR   Pfam; PF04732; Filament_head; 1.
DR   PRINTS; PR01248; TYPE1KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Intermediate filament; Reference proteome.
FT   CHAIN           1..453
FT                   /note="Plasticin"
FT                   /id="PRO_0000063857"
FT   DOMAIN          77..390
FT                   /note="IF rod"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01188"
FT   REGION          1..51
FT                   /note="Head"
FT   REGION          71..112
FT                   /note="Coil 1A"
FT   REGION          113..126
FT                   /note="Linker 1"
FT   REGION          127..222
FT                   /note="Coil 1B"
FT   REGION          223..245
FT                   /note="Linker 12"
FT   REGION          246..391
FT                   /note="Coil 2"
FT   REGION          392..453
FT                   /note="Tail"
FT   REGION          421..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   453 AA;  52635 MW;  097E486138C15D36 CRC64;
     MSHSTFSHLF SPHFGAPVYS PVSSRIGGRY VSSSVPTRSV DFRSRSSAPA PRLSYDKVDF
     SSAEAINQEF FATRSNEKRE LQELNDRFAS FIEKVRHLEQ QNSKLILELG QYKDQHQGST
     GRINELCQQE MRELRRQLEL MAKDRDQMQV ERDNLAEDVA LLNQRLNEEM GKRQEAENNL
     TLFRKDVDDA TLARLELERK IESLMDEIEF LKKMHDEEIQ DVQVSVQSQQ MKMEVMETSS
     RPDLTGALRD IRAQYESIAT KNMQESEEWY KSKFADLTDS AKRNAEAMRQ GKQENNDLRR
     QIQAQNCDID SLKRTNEALL RQMREMEEQF AAEARNYQDT VSRLEDEIRN LKEEMSRHLR
     EYQDLLNVKM ALDIEIATYR KLLEGEENRI VVPIMKMPSM SGYSGDYGQF SDTRAGQKVV
     IKTVETRDGE VVKESTKEKG RDEKKDSHGQ GKD