PLT4_ARATH
ID PLT4_ARATH Reviewed; 526 AA.
AC Q0WUU6; Q9SKT9;
DT 14-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Probable polyol transporter 4;
GN Name=PLT4; OrderedLocusNames=At2g20780; ORFNames=F5H14.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: Plasma membrane sugar-proton symporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD20917.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006234; AAD20917.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC07069.1; -; Genomic_DNA.
DR EMBL; AK227042; BAE99102.1; -; mRNA.
DR PIR; C84593; C84593.
DR RefSeq; NP_179671.2; NM_127643.5.
DR AlphaFoldDB; Q0WUU6; -.
DR SMR; Q0WUU6; -.
DR BioGRID; 1960; 8.
DR IntAct; Q0WUU6; 4.
DR STRING; 3702.AT2G20780.1; -.
DR iPTMnet; Q0WUU6; -.
DR PaxDb; Q0WUU6; -.
DR PRIDE; Q0WUU6; -.
DR ProteomicsDB; 234973; -.
DR EnsemblPlants; AT2G20780.1; AT2G20780.1; AT2G20780.
DR GeneID; 816607; -.
DR Gramene; AT2G20780.1; AT2G20780.1; AT2G20780.
DR KEGG; ath:AT2G20780; -.
DR Araport; AT2G20780; -.
DR TAIR; locus:2051443; AT2G20780.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q0WUU6; -.
DR OMA; WIDFALF; -.
DR OrthoDB; 326501at2759; -.
DR PhylomeDB; Q0WUU6; -.
DR PRO; PR:Q0WUU6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q0WUU6; baseline and differential.
DR Genevisible; Q0WUU6; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR CDD; cd17437; MFS_PLT; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR044776; PLT1-6.
DR InterPro; IPR045262; STP/PLT_plant.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23500; PTHR23500; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..526
FT /note="Probable polyol transporter 4"
FT /id="PRO_0000259872"
FT TRANSMEM 63..83
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 215..235
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 300..320
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 340..360
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 371..391
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 395..415
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..457
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 465..485
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 28..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 56801 MW; ADDB1EC9646E8239 CRC64;
MMKNLPEVGN GGGSGFPAVS VGNKKNKYQR MDSDAEESQN HREAEARNSR TRKYVMACAF
FASLNNVLLG YDVGVMSGAV LFIQQDLKIT EVQTEVLIGS LSIISLFGSL AGGRTSDSIG
RKWTMALAAL VFQTGAAVMA VAPSFEVLMI GRTLAGIGIG LGVMIAPVYI AEISPTVARG
FFTSFPEIFI NLGILLGYVS NYAFSGLSVH ISWRIMLAVG ILPSVFIGFA LCVIPESPRW
LVMKGRVDSA REVLMKTNER DDEAEERLAE IQLAAAHTEG SEDRPVWREL LSPSPVVRKM
LIVGFGIQCF QQITGIDATV YYSPEILKEA GIQDETKLLA ATVAVGVTKT VFILFATFLI
DSVGRKPLLY VSTIGMTLCL FCLSFTLTFL GQGTLGITLA LLFVCGNVAF FSIGMGPVCW
VLTSEIFPLR LRAQASALGA VGNRVCSGLV AMSFLSVSRA ITVGGTFFVF SLVSALSVIF
VYVLVPETSG KSLEQIELMF QGGLERKDGE VELGDAERLV RKEQEF
