ID   PM47A_CANBO             Reviewed;         423 AA.
AC   P21245;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Peroxisomal membrane protein PMP47A;
GN   Name=PMP47A;
OS   Candida boidinii (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Ogataea; Ogataea/Candida clade.
OX   NCBI_TaxID=5477;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=ATCC 32195;
RX   PubMed=2243083; DOI=10.1016/s0021-9258(17)30475-1;
RA   McCammon M.T., Dowds C.A., Orth K., Moomaw C.R., Slaughter C.A.,
RA   Goodman J.M.;
RT   "Sorting of peroxisomal membrane protein PMP47 from Candida boidinii into
RT   peroxisomal membranes of Saccharomyces cerevisiae.";
RL   J. Biol. Chem. 265:20098-20105(1990).
RN   [2]
RP   SIMILARITY TO MITOCHONDRIAL CARRIER FAMILY.
RX   PubMed=8291088; DOI=10.1016/0968-0004(93)90141-9;
RA   Jank B., Habermann B., Schweyen R.J., Link T.A.;
RT   "PMP47, a peroxisomal homologue of mitochondrial solute carrier proteins.";
RL   Trends Biochem. Sci. 18:427-428(1993).
CC   -!- FUNCTION: May have transport activity.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane; Multi-pass membrane protein.
CC   -!- DOMAIN: Lacks a typical peroxisomal sorting signal.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; J05672; AAA63791.1; -; Genomic_DNA.
DR   PIR; A23667; A23667.
DR   AlphaFoldDB; P21245; -.
DR   SMR; P21245; -.
DR   OrthoDB; 1186395at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Membrane; Peroxisome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..423
FT                   /note="Peroxisomal membrane protein PMP47A"
FT                   /id="PRO_0000090707"
FT   TRANSMEM        12..32
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..265
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          6..120
FT                   /note="Solcar 1"
FT   REPEAT          142..230
FT                   /note="Solcar 2"
FT   REPEAT          239..373
FT                   /note="Solcar 3"
FT   REGION          43..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..306
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  46873 MW;  09DD8A2FDBB4F279 CRC64;
     MSTREYDDLS HAFAGAGGGL LSMTLTYPLV TLTTHAQTMV KLKKDQEKEK ENSNEDGSLS
     PKSSNTSDVS QKKISQFEIL KKILKDQGAK GLYNGLESAL FGIAVTNFVY YYFYELTGKT
     LNRRSNPQTA SNSKKVALKK GLSVWQSMAA GAVAGTISRV ATNPIWVANT RMTILSKNQG
     KLGKLNTIEA IIYILKNEGW QKLFTGIVPA LFLVLNPIIQ YTIFEQLKSF IVKIKKRNIT
     PVDALLLGAF GKLIATIITY PYITLRSRMH VKSMTEISED VEKERTDSVQ SLPEDGSDED
     NLKENSAKSP YAETITKIIS KLPSPIVSMF TLGYGMYKEE GVSSFYRGLS VKLLQSILNA
     AFLFYFKEEL LILSDGIIKS TKRATGLANN PYNAKDVIHS FEKALSMRSP RTRTTTVASS
     AKE