ID   PMBA_BUCAI              Reviewed;         446 AA.
AC   P57191;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Metalloprotease PmbA homolog;
DE            EC=3.4.-.-;
GN   Name=pmbA; OrderedLocusNames=BU089;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: Probable metalloprotease. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family. {ECO:0000305}.
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DR   EMBL; BA000003; BAB12809.1; -; Genomic_DNA.
DR   RefSeq; NP_239923.1; NC_002528.1.
DR   RefSeq; WP_010895940.1; NC_002528.1.
DR   AlphaFoldDB; P57191; -.
DR   SMR; P57191; -.
DR   STRING; 107806.10038774; -.
DR   EnsemblBacteria; BAB12809; BAB12809; BAB12809.
DR   KEGG; buc:BU089; -.
DR   PATRIC; fig|107806.10.peg.97; -.
DR   eggNOG; COG0312; Bacteria.
DR   HOGENOM; CLU_026425_0_0_6; -.
DR   OMA; YLYARAE; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; -; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   Pfam; PF01523; PmbA_TldD; 1.
DR   Pfam; PF19289; PmbA_TldD_C; 1.
DR   Pfam; PF19290; PmbA_TldD_M; 1.
DR   SUPFAM; SSF111283; SSF111283; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Metalloprotease; Protease; Reference proteome.
FT   CHAIN           1..446
FT                   /note="Metalloprotease PmbA homolog"
FT                   /id="PRO_0000142348"
SQ   SEQUENCE   446 AA;  50402 MW;  4E6027D1C45213B2 CRC64;
     MQLIKEIENE ELHLVNTVKN TLKLSKNINA SVEVFIKKTI GISVNVRNNV VENVEFNSDG
     GLFITVYNKF SKGSVSSKDF SIKNIKNMLD IAINISKYSS SDFFSGLPDI KFLCFHSMEL
     DLFHPWEFNI ENAIKMSILS EKSAFESDKR IVNSEGSFLN SHTTINVFGN SLGVLEKYKS
     TRYSNYTCMI AKDKNSMQRD FDYSLSRRID DLIKPEILGQ KTAKRAISRL GSRKIQTMRS
     PIIFSSEISH MFFSHLASAI SGDNVYQKST FLINDLKMKI FPDWLDIEEN PHLKRGLGSK
     PFDNEGVATE IKYIIKAGIL QTWLLNCYNA RKLKLDSTGN CGGIHNWLVS NQNISFEELL
     KKMDQGILVT ELMGQGVDII NGNYSRGAVG FWVEKGKISY PINEITISGN LRNMWNNIVS
     ISSDVDRRNN IQCGSVLLSE IQVSGN