ID   PMBA_BUCAP              Reviewed;         447 AA.
AC   Q8KA30;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Metalloprotease PmbA homolog;
DE            EC=3.4.-.-;
GN   Name=pmbA; OrderedLocusNames=BUsg_082;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: Probable metalloprotease. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family. {ECO:0000305}.
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DR   EMBL; AE013218; AAM67652.1; -; Genomic_DNA.
DR   RefSeq; WP_011053618.1; NC_004061.1.
DR   AlphaFoldDB; Q8KA30; -.
DR   SMR; Q8KA30; -.
DR   STRING; 198804.BUsg_082; -.
DR   PRIDE; Q8KA30; -.
DR   EnsemblBacteria; AAM67652; AAM67652; BUsg_082.
DR   KEGG; bas:BUsg_082; -.
DR   eggNOG; COG0312; Bacteria.
DR   HOGENOM; CLU_026425_0_0_6; -.
DR   OMA; YLYARAE; -.
DR   OrthoDB; 958356at2; -.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; -; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   Pfam; PF19289; PmbA_TldD_C; 1.
DR   Pfam; PF19290; PmbA_TldD_M; 1.
DR   SUPFAM; SSF111283; SSF111283; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Metalloprotease; Protease.
FT   CHAIN           1..447
FT                   /note="Metalloprotease PmbA homolog"
FT                   /id="PRO_0000142349"
SQ   SEQUENCE   447 AA;  50319 MW;  7C19C6846254C85E CRC64;
     MQLLNQIEKE ENLLIEKVKN TLFLAQEKVN CSIEVCVKKT IGISVNIRNS IVENVEFNND
     SILFVTVYNK FSKGVSSSKD FSTNGIKKML EIAIDISKHT SSDFFSGLPD AKFLCFKAQD
     LDLFYPSEFN IKNAINFASE SEREAFKFDK RIINSEGSFF SNHITIKVFA NSLGMLEQYK
     STRYSNYNCM IAKDNSTMQR DFSYSTSRKL DDLEKPDVLG QKTATNAISR LGSKKINTIK
     CPVIFSKETS SIFFSHLIPA ISGDNIYRKS TFLLYDLKKR IFPEWLNIEE NPHIKKGLGS
     KPFDSEGVST TIRSIIKNGI LETWLLNTYN ARKLGLTTTG HSGGISNWLV SNKNISFKEL
     LKMMKTGLLI TELMGQGVDI VSGNYSRGAV GFWIENGKIK YPVNEITISG NLKKMWNSIL
     SISNDVNMYS NIQCGSTLLS EIQISGN