ID   PMD1_LOCMI              Reviewed;          54 AA.
AC   P80059;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Pars intercerebralis major peptide D1;
DE            Short=PMP-D1;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Pars intercerebralis;
RX   PubMed=1740125; DOI=10.1111/j.1432-1033.1992.tb16617.x;
RA   Nakakura N., Hietter H., van Dorsselaer A., Luu B.;
RT   "Isolation and structural determination of three peptides from the insect
RT   Locusta migratoria. Identification of a deoxyhexose-linked peptide.";
RL   Eur. J. Biochem. 204:147-153(1992).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Brain.
CC   -!- PTM: Six disulfide bonds are present.
CC   -!- SIMILARITY: Belongs to the granulin family. {ECO:0000305}.
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DR   PIR; S23075; S23075.
DR   AlphaFoldDB; P80059; -.
DR   SMR; P80059; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.25.160; -; 1.
DR   InterPro; IPR000118; Granulin.
DR   InterPro; IPR037277; Granulin_sf.
DR   Pfam; PF00396; Granulin; 1.
DR   SMART; SM00277; GRAN; 1.
DR   PROSITE; PS00799; GRANULINS; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Neuropeptide; Secreted.
FT   CHAIN           1..54
FT                   /note="Pars intercerebralis major peptide D1"
FT                   /id="PRO_0000150134"
SQ   SEQUENCE   54 AA;  5788 MW;  3011D739060D72F5 CRC64;
     SCTEKTCPGT ETCCTTPQGE EGCCPYKEGV CCLDGIHCCP SGTVCDEDHR RCIQ