PMP21_CHLPN
ID PMP21_CHLPN Reviewed; 1609 AA.
AC Q9Z6U5; Q9RB58;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 135.
DE RecName: Full=Probable outer membrane protein pmp21;
DE AltName: Full=Polymorphic membrane protein 21;
DE Flags: Precursor;
GN Name=pmp21; OrderedLocusNames=CPn_0963, CP_0897, CpB1000;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Cell outer membrane
CC {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Extracellular
CC side {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Elementary body.
CC -!- SIMILARITY: Belongs to the PMP outer membrane protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAP98929.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE001363; AAD19099.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF38684.1; -; Genomic_DNA.
DR EMBL; BA000008; BAA99171.1; -; Genomic_DNA.
DR EMBL; AE009440; AAP98929.1; ALT_INIT; Genomic_DNA.
DR PIR; A86611; A86611.
DR PIR; H72013; H72013.
DR RefSeq; NP_225156.1; NC_000922.1.
DR RefSeq; WP_010883596.1; NZ_LN847257.1.
DR AlphaFoldDB; Q9Z6U5; -.
DR STRING; 115711.CP_0897; -.
DR EnsemblBacteria; AAD19099; AAD19099; CPn_0963.
DR EnsemblBacteria; AAF38684; AAF38684; CP_0897.
DR GeneID; 45051020; -.
DR KEGG; cpa:CP_0897; -.
DR KEGG; cpj:pmp_21; -.
DR KEGG; cpn:CPn_0963; -.
DR KEGG; cpt:CpB1000; -.
DR PATRIC; fig|115713.3.peg.1054; -.
DR eggNOG; COG3210; Bacteria.
DR eggNOG; COG4625; Bacteria.
DR HOGENOM; CLU_247701_0_0_0; -.
DR OrthoDB; 11453at2; -.
DR Proteomes; UP000000583; Chromosome.
DR Proteomes; UP000000801; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.128.130; -; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR011427; Polymorphic_membr_middle.
DR InterPro; IPR003368; POMP_repeat.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF07548; ChlamPMP_M; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; SSF103515; 1.
DR TIGRFAMs; TIGR01376; POMP_repeat; 3.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Cell wall; Membrane; Secreted; Signal; Transmembrane;
KW Transmembrane beta strand.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..1609
FT /note="Probable outer membrane protein pmp21"
FT /id="PRO_0000024750"
FT DOMAIN 1328..1609
FT /note="Autotransporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00556"
FT REGION 132..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 420
FT /note="I -> M (in Ref. 3; BAA99171)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1609 AA; 170866 MW; 2604C3E9FC4024CB CRC64;
MVAKKTVRSY RSSFSHSVIV AILSAGIAFE AHSLHSSELD LGVFNKQFEE HSAHVEEAQT
SVLKGSDPVN PSQKESEKVL YTQVPLTQGS SGESLDLADA NFLEHFQHLF EETTVFGIDQ
KLVWSDLDTR NFSQPTQEPD TSNAVSEKIS SDTKENRKDL ETEDPSKKSG LKEVSSDLPK
SPETAVAAIS EDLEISENIS ARDPLQGLAF FYKNTSSQSI SEKDSSFQGI IFSGSGANSG
LGFENLKAPK SGAAVYSDRD IVFENLVKGL SFISCESLED GSAAGVNIVV THCGDVTLTD
CATGLDLEAL RLVKDFSRGG AVFTARNHEV QNNLAGGILS VVGNKGAIVV EKNSAEKSNG
GAFACGSFVY SNNENTALWK ENQALSGGAI SSASDIDIQG NCSAIEFSGN QSLIALGEHI
GLTDFVGGGA LAAQGTLTLR NNAVVQCVKN TSKTHGGAIL AGTVDLNETI SEVAFKQNTA
ALTGGALSAN DKVIIANNFG EILFEQNEVR NHGGAIYCGC RSNPKLEQKD SGENINIIGN
SGAITFLKNK ASVLEVMTQA EDYAGGGALW GHNVLLDSNS GNIQFIGNIG GSTFWIGEYV
GGGAILSTDR VTISNNSGDV VFKGNKGQCL AQKYVAPQET APVESDASST NKDEKSLNAC
SHGDHYPPKT VEEEVPPSLL EEHPVVSSTD IRGGGAILAQ HIFITDNTGN LRFSGNLGGG
EESSTVGDLA IVGGGALLST NEVNVCSNQN VVFSDNVTSN GCDSGGAILA KKVDISANHS
VEFVSNGSGK FGGAVCALNE SVNITDNGSA VSFSKNRTRL GGAGVAAPQG SVTICGNQGN
IAFKENFVFG SENQRSGGGA IIANSSVNIQ DNAGDILFVS NSTGSYGGAI FVGSLVASEG
SNPRTLTITG NSGDILFAKN STQTAASLSE KDSFGGGAIY TQNLKIVKNA GNVSFYGNRA
PSGAGVQIAD GGTVCLEAFG GDILFEGNIN FDGSFNAIHL CGNDSKIVEL SAVQDKNIIF
QDAITYEENT IRGLPDKDVS PLSAPSLIFN SKPQDDSAQH HEGTIRFSRG VSKIPQIAAI
QEGTLALSQN AELWLAGLKQ ETGSSIVLSA GSILRIFDSQ VDSSAPLPTE NKEETLVSAG
VQINMSSPTP NKDKAVDTPV LADIISITVD LSSFVPEQDG TLPLPPEIII PKGTKLHSNA
IDLKIIDPTN VGYENHALLS SHKDIPLISL KTAEGMTGTP TADASLSNIK IDVSLPSITP
ATYGHTGVWS ESKMEDGRLV VGWQPTGYKL NPEKQGALVL NNLWSHYTDL RALKQEIFAH
HTIAQRMELD FSTNVWGSGL GVVEDCQNIG EFDGFKHHLT GYALGLDTQL VEDFLIGGCF
SQFFGKTESQ SYKAKNDVKS YMGAAYAGIL AGPWLIKGAF VYGNINNDLT TDYGTLGIST
GSWIGKGFIA GTSIDYRYIV NPRRFISAIV STVVPFVEAE YVRIDLPEIS EQGKEVRTFQ
KTRFENVAIP FGFALEHAYS RGSRAEVNSV QLAYVFDVYR KGPVSLITLK DAAYSWKSYG
VDIPCKAWKA RLSNNTEWNS YLSTYLAFNY EWREDLIAYD FNGGIRIIF
