PMP3_NEUCR
ID PMP3_NEUCR Reviewed; 57 AA.
AC Q871V2;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Plasma membrane proteolipid 3;
GN Name=pmp-1; Synonyms=pmp3; ORFNames=100H1.040, NCU06660;
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12655011; DOI=10.1093/nar/gkg293;
RA Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT genome sequence.";
RL Nucleic Acids Res. 31:1944-1954(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Plays a role in the regulation of membrane potential. Could
CC mediate a proton leak (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0057 (PMP3) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA31469.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; BX294019; CAD70889.1; -; Genomic_DNA.
DR EMBL; CM002240; EAA31469.2; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_960705.2; XM_955612.3.
DR AlphaFoldDB; Q871V2; -.
DR STRING; 367110.Q871V2; -.
DR EnsemblFungi; EAA31469; EAA31469; NCU06660.
DR GeneID; 3876843; -.
DR KEGG; ncr:NCU06660; -.
DR HOGENOM; CLU_107649_6_2_1; -.
DR InParanoid; Q871V2; -.
DR OMA; VHAIWVI; -.
DR Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000612; PMP3.
DR PANTHER; PTHR21659; PTHR21659; 1.
DR Pfam; PF01679; Pmp3; 1.
DR PROSITE; PS01309; UPF0057; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..57
FT /note="Plasma membrane proteolipid 3"
FT /id="PRO_0000247913"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 57 AA; 6225 MW; 94D4415A11EEDE27 CRC64;
MAFTASDICK IIVAVILPPL GVFFERGCGA DLFINILLTI LGYLPGIVHA LYIILKY