ID   PMPA_CHLTR              Reviewed;         975 AA.
AC   O84417;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Probable outer membrane protein PmpA;
DE   AltName: Full=Polymorphic membrane protein A;
DE   Flags: Precursor;
GN   Name=pmpA; OrderedLocusNames=CT_412;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall. Cell outer membrane
CC       {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Extracellular
CC       side {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Elementary body.
CC   -!- SIMILARITY: Belongs to the PMP outer membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE001273; AAC68009.1; -; Genomic_DNA.
DR   PIR; F71518; F71518.
DR   RefSeq; NP_219922.1; NC_000117.1.
DR   RefSeq; WP_010725190.1; NC_000117.1.
DR   AlphaFoldDB; O84417; -.
DR   STRING; 813.O172_02235; -.
DR   TCDB; 1.B.12.1.7; the autotransporter-1 (at-1) family.
DR   PRIDE; O84417; -.
DR   EnsemblBacteria; AAC68009; AAC68009; CT_412.
DR   GeneID; 884704; -.
DR   KEGG; ctr:CT_412; -.
DR   PATRIC; fig|272561.5.peg.443; -.
DR   HOGENOM; CLU_004549_1_1_0; -.
DR   OMA; HEYASKP; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0016579; P:protein deubiquitination; IBA:GO_Central.
DR   InterPro; IPR005546; Autotransporte_beta.
DR   InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR   InterPro; IPR011427; Polymorphic_membr_middle.
DR   InterPro; IPR003368; POMP_repeat.
DR   Pfam; PF02415; Chlam_PMP; 3.
DR   Pfam; PF07548; ChlamPMP_M; 1.
DR   SUPFAM; SSF103515; SSF103515; 1.
DR   TIGRFAMs; TIGR01376; POMP_repeat; 4.
DR   PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Cell wall; Membrane; Reference proteome; Secreted;
KW   Signal; Transmembrane; Transmembrane beta strand.
FT   SIGNAL          1..51
FT                   /evidence="ECO:0000255"
FT   CHAIN           52..975
FT                   /note="Probable outer membrane protein PmpA"
FT                   /id="PRO_0000024717"
FT   DOMAIN          699..975
FT                   /note="Autotransporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00556"
SQ   SEQUENCE   975 AA;  105649 MW;  7138BB9ED1E82C14 CRC64;
     MNRVIEIHAH YDQRQLSQSP NTNFLVHHPY LTLIPKFLLG ALIVYAPYSF AEMELAISGH
     KQGKDRDTFT MISSCPEGTN YIINRKLILS DFSLLNKVSS GGAFRNLAGK ISFLGKNSSA
     SIHFKHININ GFGAGVFSES SIEFTDLRKL VAFGSESTGG IFTAKEDISF KNNHHIAFRN
     NITKGNGGVI QLQGDMKGSV SFVDQRGAII FTNNQAVTSS SMKHSGRGGA ISGDFAGSRI
     LFLNNQQITF EGNSAVHGGA IYNKNGLVEF LGNAGPLAFK ENTTIANGGA IYTSNFKANQ
     QTSPILFSQN HANKKGGAIY AQYVNLEQNQ DTIRFEKNTA KEGGGAITSS QCSITAHNTI
     IFSDNAAGDL GGGAILLEGK KPSLTLIAHS GNIAFSGNTM LHITKKASLD RHNSILIKEA
     PYKIQLAANK NHSIHFFDPV MALSASSSPI QINAPEYETP FFSPKGMIVF SGANLLDDAR
     EDVANRTSIF NQPVHLYNGT LSIENGAHLI VQSFKQTGGR ISLSPGSSLA LYTMNSFFHG
     NISSKEPLEI NGLSFGVDIS PSNLQAEIRA GNAPLRLSGS PSIHDPEGLF YENRDTAASP
     YQMEILLTSD KIVDISKFTT DSLVTNKQSG FQGAWHFSWQ PNTINNTKQK ILRASWLPTG
     EYVLESNRVG RAVPNSLWST FLLLQTASHN LGDHLCNNRS LIPTSYFGVL IGGTGAEMST
     HSSEEESFIS RLGATGTSII RLTPSLTLSG GGSHMFGDSF VADLPEHITS EGIVQNVGLT
     HVWGPLTVNS TLCAALDHNA MVRICSKKDH TYGKWDTFGM RGTLGASYTF LEYDQTMRVF
     SFANIEATNI LQRAFTETGY NPRSFSKTKL LNIAIPIGIG YEFCLGNSSF ALLGKGSIGY
     SRDIKRENPS TLAHLAMNDF AWTTNGCSVP TSAHTLANQL ILRYKACSLY ITAYTINREG
     KNLSNSLSCG GYVGF