PMPH_CHLTR
ID PMPH_CHLTR Reviewed; 1016 AA.
AC O84880;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Probable outer membrane protein PmpH;
DE AltName: Full=Polymorphic membrane protein H;
DE Flags: Precursor;
GN Name=pmpH; OrderedLocusNames=CT_872;
OS Chlamydia trachomatis (strain D/UW-3/Cx).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=272561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D/UW-3/Cx;
RX PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT trachomatis.";
RL Science 282:754-759(1998).
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Cell outer membrane
CC {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Extracellular
CC side {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Elementary body.
CC -!- SIMILARITY: Belongs to the PMP outer membrane protein family.
CC {ECO:0000305}.
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DR EMBL; AE001273; AAC68470.1; -; Genomic_DNA.
DR PIR; H71460; H71460.
DR RefSeq; NP_220394.1; NC_000117.1.
DR RefSeq; WP_010725378.1; NC_000117.1.
DR AlphaFoldDB; O84880; -.
DR STRING; 813.O172_04875; -.
DR EnsemblBacteria; AAC68470; AAC68470; CT_872.
DR GeneID; 884673; -.
DR KEGG; ctr:CT_872; -.
DR PATRIC; fig|272561.5.peg.963; -.
DR HOGENOM; CLU_004549_2_0_0; -.
DR OMA; WHNNSYY; -.
DR Proteomes; UP000000431; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR011427; Polymorphic_membr_middle.
DR InterPro; IPR003368; POMP_repeat.
DR Pfam; PF02415; Chlam_PMP; 2.
DR Pfam; PF07548; ChlamPMP_M; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; SSF103515; 1.
DR TIGRFAMs; TIGR01376; POMP_repeat; 3.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Cell wall; Membrane; Reference proteome; Secreted;
KW Signal; Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..1016
FT /note="Probable outer membrane protein PmpH"
FT /id="PRO_0000024731"
FT DOMAIN 697..1016
FT /note="Autotransporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00556"
SQ SEQUENCE 1016 AA; 107905 MW; E691912C3A2BD6F7 CRC64;
MPFSLRSTSF CFLACLCSYS YGFASSPQVL TPNVTTPFKG DDVYLNGDCA FVNVYAGAEN
GSIISANGDN LTITGQNHTL SFTDSQGPVL QNYAFISAGE TLTLKDFSSL MFSKNVSCGE
KGMISGKTVS ISGAGEVIFW DNSVGYSPLS IVPASTPTPP APAPAPAASS SLSPTVSDAR
KGSIFSVETS LEISGVKKGV MFDNNAGNFG TVFRGNSNNN AGSGGSGSAT TPSFTVKNCK
GKVSFTDNVA SCGGGVVYKG TVLFKDNEGG IFFRGNTAYD DLGILAATSR DQNTETGGGG
GVICSPDDSV KFEGNKGSIV FDYNFAKGRG GSILTKEFSL VADDSVVFSN NTAEKGGGAI
YAPTIDISTN GGSILFERNR AAEGGAICVS EASSGSTGNL TLSASDGDIV FSGNMTSDRP
GERSAARILS DGTTVSLNAS GLSKLIFYDP VVQNNSAAGA STPSPSSSSM PGAVTINQSG
NGSVIFTAES LTPSEKLQVL NSTSNFPGAL TVSGGELVVT EGATLTTGTI TATSGRVTLG
SGASLSAVAG AANNNYTCTV SKLGIDLESF LTPNYKTAIL GADGTVTVNS GSTLDLVMES
EAEVYDNPLF VGSLTIPFVT LSSSSASNGV TKNSVTINDA DAAHYGYQGS WSADWTKPPL
APDAKGMVPP NTNNTLYLTW RPASNYGEYR LDPQRKGELV PNSLWVAGSA LRTFTNGLKE
HYVSRDVGFV ASLHALGDYI LNYTQDDRDG FLARYGGFQA TAASHYENGS IFGVAFGQLY
GQTKSRMYYS KDAGNMTMLS CFGRSYVDIK GTETVMYWET AYGYSVHRMH TQYFNDKTQK
FDHSKCHWHN NNYYAFVGAE HNFLEYCIPT RQFARDYELT GFMRFEMAGG WSSSTRETGS
LTRYFARGSG HNMSLPIGIV AHAVSHVRRS PPSKLTLNMG YRPDIWRVTP HCNMEIIANG
VKTPIQGSPL ARHAFFLEVH DTLYIHHFGR AYMNYSLDAR RRQTAHFVSM GLNRIF