ID   PMPR_PSEAE              Reviewed;         248 AA.
AC   Q51423;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Transcriptional regulatory protein PmpR;
GN   Name=pmpR; OrderedLocusNames=PA0964;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=8982068; DOI=10.1016/s0378-1119(96)00474-x;
RA   Hishida T., Iwasaki H., Ishioka K., Shinagawa H.;
RT   "Molecular analysis of the Pseudomonas aeruginosa genes, ruvA, ruvB and
RT   ruvC, involved in processing of homologous recombination intermediates.";
RL   Gene 182:63-70(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [3]
RP   FUNCTION, DNA-BINDING, AND GENE NAME.
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=18641136; DOI=10.1128/jb.00428-08;
RA   Liang H., Li L., Dong Z., Surette M.G., Duan K.;
RT   "The YebC family protein PA0964 negatively regulates the Pseudomonas
RT   aeruginosa quinolone signal system and pyocyanin production.";
RL   J. Bacteriol. 190:6217-6227(2008).
CC   -!- FUNCTION: Involved in regulation of the quinolone signal (PQS) system
CC       and of pyocyanine production. Negatively regulates the quorum-sensing
CC       response regulator pqsR of the PQS system by binding to its promoter
CC       region. {ECO:0000269|PubMed:18641136}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00693}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D83138; BAA11816.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG04353.1; -; Genomic_DNA.
DR   PIR; F83524; F83524.
DR   PIR; JC5479; JC5479.
DR   RefSeq; NP_249655.1; NC_002516.2.
DR   RefSeq; WP_003086107.1; NZ_QZGE01000007.1.
DR   AlphaFoldDB; Q51423; -.
DR   SMR; Q51423; -.
DR   STRING; 287.DR97_973; -.
DR   PaxDb; Q51423; -.
DR   PRIDE; Q51423; -.
DR   EnsemblBacteria; AAG04353; AAG04353; PA0964.
DR   GeneID; 882153; -.
DR   KEGG; pae:PA0964; -.
DR   PATRIC; fig|208964.12.peg.1002; -.
DR   PseudoCAP; PA0964; -.
DR   HOGENOM; CLU_062974_2_2_6; -.
DR   InParanoid; Q51423; -.
DR   OMA; ETIMYEG; -.
DR   PhylomeDB; Q51423; -.
DR   BioCyc; PAER208964:G1FZ6-985-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0071281; P:cellular response to iron ion; EXP:CollecTF.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..248
FT                   /note="Transcriptional regulatory protein PmpR"
FT                   /id="PRO_0000175868"
FT   CONFLICT        14
FT                   /note="K -> E (in Ref. 1; BAA11816)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   248 AA;  26557 MW;  68783EE0C0E02523 CRC64;
     MAGHSKWANI KHRKERQDAK KGKIFTKLIR ELTVAARQGG GVPADNPRLR LAVDKALTAN
     MTRDTIDRAI ARGVGSNDAD NMVELSYEGY APSGVAIIVE AMTDNRNRTA AEVRHAFSKC
     GGNLGTDGSV AYMFERKGQI SFAPGVDEEA LMDAALEAGA DDVVVNDDGS IDVFTTFADF
     ISVNEALAAA GFKGDEAEVT MIPSTTATLD LETAQKVLKL IDMLEDLDDV QNVYSNADIP
     DDVMAQLG