PMT12_ARATH
ID PMT12_ARATH Reviewed; 378 AA.
AC Q8RWB7;
DT 10-FEB-2021, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Probable methyltransferase At1g29790 {ECO:0000305};
DE EC=2.1.1.- {ECO:0000305};
GN Name=CLSC5 {ECO:0000312|EMBL:AEE31129.1};
GN OrderedLocusNames=At1g29790 {ECO:0000312|Araport:AT1G29790};
GN ORFNames=F1N18.26 {ECO:0000312|EMBL:AEE31129.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-
CC pass type II membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; AC008030; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE31129.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31130.1; -; Genomic_DNA.
DR EMBL; AY093204; AAM13203.1; -; mRNA.
DR EMBL; BT008461; AAP37820.1; -; mRNA.
DR RefSeq; NP_001117383.1; NM_001123911.4.
DR RefSeq; NP_174272.2; NM_102719.7.
DR AlphaFoldDB; Q8RWB7; -.
DR PaxDb; Q8RWB7; -.
DR PRIDE; Q8RWB7; -.
DR ProteomicsDB; 187582; -.
DR EnsemblPlants; AT1G29790.1; AT1G29790.1; AT1G29790.
DR EnsemblPlants; AT1G29790.2; AT1G29790.2; AT1G29790.
DR GeneID; 839857; -.
DR Gramene; AT1G29790.1; AT1G29790.1; AT1G29790.
DR Gramene; AT1G29790.2; AT1G29790.2; AT1G29790.
DR KEGG; ath:AT1G29790; -.
DR Araport; AT1G29790; -.
DR TAIR; locus:2019312; AT1G29790.
DR eggNOG; ENOG502QVGT; Eukaryota.
DR HOGENOM; CLU_025910_0_1_1; -.
DR InParanoid; Q8RWB7; -.
DR OMA; YMSYTPF; -.
DR OrthoDB; 847406at2759; -.
DR PhylomeDB; Q8RWB7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8RWB7; baseline and differential.
DR GO; GO:0005768; C:endosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0005797; C:Golgi medial cisterna; HDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Golgi apparatus; Membrane; Methyltransferase;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..378
FT /note="Probable methyltransferase At1g29790"
FT /id="PRO_5014312305"
FT TOPO_DOM 1..6
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 7..29
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30..378
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT REGION 67..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 247
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 378 AA; 41956 MW; 1238914E6EA69B03 CRC64;
MAGFTMSLNL LLLVAMVATN ILSLYHLSST TNFFQSTVKS SQSSVPTVPD HLLRQLHTIR
AAINHLTTHQ PDKSTSTSTS RAAVSSSSSS TAPKELLIYS KLSPIASACH NYPDLLHEYM
NYTPFSLCPS DTDLVEKLIL RGCHPLPRRR CFSRTPRNPS DSKPESNVLW SYYSCKSFDC
LITKFSDLGF DLSLEKSKSQ FSAYKSELDL PISQLLQIAK SANSVLRLGI DVGGGTGSFA
AAMKARNVTV LTTTMNFNAP YSEAVAMRGL VPLHVPLQQR LPVFDGVVDL VRCGRAVNRW
IPVTVMEFFF FDLDRILRGG GYLWLDRFFS KKVDLENVYA PMIGKLGYKK VKWAVANKAD
SKHGEVFLTA LLQKPVAR
