PMTA_ARATH
ID PMTA_ARATH Reviewed; 655 AA.
AC Q94KE1; O80659;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Probable methyltransferase PMT10;
DE EC=2.1.1.-;
GN OrderedLocusNames=At1g77260; ORFNames=T14N5.11, T14N5.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=17461780; DOI=10.1111/j.1365-313x.2007.03123.x;
RA Krupkova E., Immerzeel P., Pauly M., Schmulling T.;
RT "The TUMOROUS SHOOT DEVELOPMENT2 gene of Arabidopsis encoding a putative
RT methyltransferase is required for cell adhesion and co-ordinated plant
RT development.";
RL Plant J. 50:735-750(2007).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type II membrane protein.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC34356.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC004260; AAC34356.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35955.1; -; Genomic_DNA.
DR EMBL; AF367259; AAK56248.1; -; mRNA.
DR EMBL; AY093963; AAM16224.1; -; mRNA.
DR PIR; T00454; T00454.
DR RefSeq; NP_565153.1; NM_106375.2.
DR AlphaFoldDB; Q94KE1; -.
DR PaxDb; Q94KE1; -.
DR PRIDE; Q94KE1; -.
DR ProteomicsDB; 234987; -.
DR EnsemblPlants; AT1G77260.1; AT1G77260.1; AT1G77260.
DR GeneID; 844062; -.
DR Gramene; AT1G77260.1; AT1G77260.1; AT1G77260.
DR KEGG; ath:AT1G77260; -.
DR Araport; AT1G77260; -.
DR TAIR; locus:2195955; AT1G77260.
DR eggNOG; ENOG502QW24; Eukaryota.
DR HOGENOM; CLU_010485_2_4_1; -.
DR InParanoid; Q94KE1; -.
DR OMA; MLHETGE; -.
DR OrthoDB; 366627at2759; -.
DR PhylomeDB; Q94KE1; -.
DR PRO; PR:Q94KE1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q94KE1; baseline and differential.
DR Genevisible; Q94KE1; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000138; C:Golgi trans cisterna; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10108; PTHR10108; 1.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; SSF53335; 2.
PE 2: Evidence at transcript level;
KW Glycoprotein; Golgi apparatus; Membrane; Methyltransferase;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..655
FT /note="Probable methyltransferase PMT10"
FT /id="PRO_0000393250"
FT TOPO_DOM 1..15
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 16..36
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 37..655
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT CARBOHYD 54
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 62
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 125
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 167
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 288
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 342
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 411
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 456
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 592
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 655 AA; 74448 MW; 256C36A891F23460 CRC64;
MKLSDVGLDV VKTPRLVKLI AFAFLSISTI FLFNHFSDSF SYPSLPFPIS SSSNVTEAIQ
TNITSVAAVA PSPPPRPRLK ISPPPLPPTV VRTGIINENG AMSDSFEIGG FDPDSIDELK
SATGNSSVEE KESPEVGFQI EKLKLCDKTK IDYIPCLDNE EEIKRLNNTD RGENYERHCP
KQSLDCLIPP PDGYKKPIQW PQSRDKIWFN NVPHTRLVED KGGQNWIRRE KDKFVFPGGG
TQFIHGADQY LDQISQMIPD ITFGSRTRVA LDIGCGVASF GAFLMQRNTT TLSVAPKDVH
ENQIQFALER GVPAMVAVFA TRRLLYPSQS FEMIHCSRCR INWTRDDGIL LLEVNRMLRA
GGYFVWAAQP VYKHEDNLQE QWKEMLDLTN RICWELIKKE GYIAVWRKPL NNSCYVSREA
GTKPPLCRPD DDPDDVWYVD MKPCITRLPD NGYGANVSTW PARLHDPPER LQSIQMDAYI
SRKEIMKAES RFWLEVVESY VRVFRWKEFK LRNVLDMRAG FGGFAAALND LGLDCWVMNI
VPVSGFNTLP VIYDRGLQGA MHDWCEPFDT YPRTYDLIHA AFLFSVEKKR CNITNIMLEM
DRMLRPGGHV YIRDSLSLMD QLQQVAKAIG WTAGVHDTGE GPHASVRILI CDKRI
