PMTB_ARATH
ID PMTB_ARATH Reviewed; 694 AA.
AC O22285;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Probable methyltransferase PMT11;
DE EC=2.1.1.-;
GN OrderedLocusNames=At2g39750; ORFNames=T5I7.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=17461780; DOI=10.1111/j.1365-313x.2007.03123.x;
RA Krupkova E., Immerzeel P., Pauly M., Schmulling T.;
RT "The TUMOROUS SHOOT DEVELOPMENT2 gene of Arabidopsis encoding a putative
RT methyltransferase is required for cell adhesion and co-ordinated plant
RT development.";
RL Plant J. 50:735-750(2007).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type II membrane protein.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; AC003000; AAB87124.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09718.1; -; Genomic_DNA.
DR EMBL; AY053416; AAK96646.1; -; mRNA.
DR EMBL; AY124857; AAM70566.1; -; mRNA.
DR PIR; T01005; T01005.
DR RefSeq; NP_030521.1; NM_129533.4.
DR AlphaFoldDB; O22285; -.
DR BioGRID; 3898; 2.
DR IntAct; O22285; 2.
DR STRING; 3702.AT2G39750.1; -.
DR PaxDb; O22285; -.
DR PRIDE; O22285; -.
DR ProteomicsDB; 234746; -.
DR EnsemblPlants; AT2G39750.1; AT2G39750.1; AT2G39750.
DR GeneID; 818560; -.
DR Gramene; AT2G39750.1; AT2G39750.1; AT2G39750.
DR KEGG; ath:AT2G39750; -.
DR Araport; AT2G39750; -.
DR TAIR; locus:2063947; AT2G39750.
DR eggNOG; ENOG502QQFS; Eukaryota.
DR HOGENOM; CLU_010485_2_4_1; -.
DR InParanoid; O22285; -.
DR OMA; KFDSYIA; -.
DR OrthoDB; 366627at2759; -.
DR PhylomeDB; O22285; -.
DR PRO; PR:O22285; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22285; baseline and differential.
DR Genevisible; O22285; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10108; PTHR10108; 1.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; SSF53335; 2.
PE 2: Evidence at transcript level;
KW Glycoprotein; Golgi apparatus; Membrane; Methyltransferase;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..694
FT /note="Probable methyltransferase PMT11"
FT /id="PRO_0000393251"
FT TOPO_DOM 1..14
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..32
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 33..694
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT REGION 83..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..125
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 69
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 77
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 155
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 378
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 423
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 694 AA; 78369 MW; 3056F74EB053D1A1 CRC64;
MKPLTNGDLF KSPTLIKISA LVFVTVAFFY LGKHWSDDGY QQLVFFSSST SGSSIPEVSV
SPNSNRVFNL SAIIPTNHTQ IEIPATIRQQ PPSVVADTEK VKVEANPPPP PPPSPSPPPP
PGPVKSFGIV DANGVMSDDF EVGEVESDTV EDWGNQTEIV EAKSDGDSKA RVRIKKFGMC
PESMREYIPC LDNTDVIKKL KSTERGERFE RHCPEKGKGL NCLVPPPKGY RQPIPWPKSR
DEVWFSNVPH TRLVEDKGGQ NWISRDKNKF KFPGGGTQFI HGADQYLDQM SKMVSDITFG
KHIRVAMDVG CGVASFGAYL LSRDVMTMSV APKDVHENQI QFALERGVPA MAAAFATRRL
LYPSQAFDLI HCSRCRINWT RDDGILLLEI NRMLRAGGYF AWAAQPVYKH EPALEEQWTE
MLNLTISLCW KLVKKEGYVA IWQKPFNNDC YLSREAGTKP PLCDESDDPD NVWYTNLKPC
ISRIPEKGYG GNVPLWPARL HTPPDRLQTI KFDSYIARKE LFKAESKYWN EIIGGYVRAL
KWKKMKLRNV LDMRAGFGGF AAALNDHKLD CWVLSVVPVS GPNTLPVIYD RGLLGVMHDW
CEPFDTYPRT YDFLHASGLF SIERKRCEMS TILLEMDRIL RPGGRAYIRD SIDVMDEIQE
ITKAMGWHTS LRDTSEGPHA SYRILTCEKR LLRA
