ID   PMTJ_ARATH              Reviewed;         611 AA.
AC   Q9ZW75; Q8S8J5;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Probable methyltransferase PMT19;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=At2g43200; ORFNames=F14B2.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=17461780; DOI=10.1111/j.1365-313x.2007.03123.x;
RA   Krupkova E., Immerzeel P., Pauly M., Schmulling T.;
RT   "The TUMOROUS SHOOT DEVELOPMENT2 gene of Arabidopsis encoding a putative
RT   methyltransferase is required for cell adhesion and co-ordinated plant
RT   development.";
RL   Plant J. 50:735-750(2007).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Single-pass type II membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM15161.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC004450; AAC64309.1; -; Genomic_DNA.
DR   EMBL; AC006224; AAM15161.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC10228.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61303.1; -; Genomic_DNA.
DR   PIR; C84863; C84863.
DR   RefSeq; NP_001318411.1; NM_001337020.1.
DR   RefSeq; NP_181849.1; NM_129882.2.
DR   AlphaFoldDB; Q9ZW75; -.
DR   STRING; 3702.AT2G43200.1; -.
DR   iPTMnet; Q9ZW75; -.
DR   PaxDb; Q9ZW75; -.
DR   PRIDE; Q9ZW75; -.
DR   ProteomicsDB; 234787; -.
DR   EnsemblPlants; AT2G43200.1; AT2G43200.1; AT2G43200.
DR   EnsemblPlants; AT2G43200.2; AT2G43200.2; AT2G43200.
DR   GeneID; 818921; -.
DR   Gramene; AT2G43200.1; AT2G43200.1; AT2G43200.
DR   Gramene; AT2G43200.2; AT2G43200.2; AT2G43200.
DR   KEGG; ath:AT2G43200; -.
DR   Araport; AT2G43200; -.
DR   TAIR; locus:2041031; AT2G43200.
DR   eggNOG; ENOG502QPN0; Eukaryota.
DR   HOGENOM; CLU_010485_2_2_1; -.
DR   InParanoid; Q9ZW75; -.
DR   OMA; MPPISWK; -.
DR   OrthoDB; 355067at2759; -.
DR   PhylomeDB; Q9ZW75; -.
DR   PRO; PR:Q9ZW75; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9ZW75; baseline and differential.
DR   Genevisible; Q9ZW75; AT.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 2.
DR   InterPro; IPR004159; Put_SAM_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR10108; PTHR10108; 1.
DR   Pfam; PF03141; Methyltransf_29; 1.
DR   SUPFAM; SSF53335; SSF53335; 2.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Methyltransferase;
KW   Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..611
FT                   /note="Probable methyltransferase PMT19"
FT                   /id="PRO_0000393259"
FT   TOPO_DOM        1..15
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        16..36
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        37..611
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        68
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        97
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        289
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        408
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        411
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        587
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   611 AA;  70236 MW;  643215132E6FE722 CRC64;
     MNPSQQHLPK LCPKRLFLFF TPFLLFSLYY ILTTIKTITI SSQDRHHPPQ LHVPSISHYY
     SLPETSENRS SPPPLLLPPP PSSSSSLSSY FPLCPKNFTN YLPCHDPSTA RQYSIERHYR
     RERHCPDIAQ EKFRCLVPKP TGYKTPFPWP ESRKYAWFRN VPFKRLAELK KTQNWVRLEG
     DRFVFPGGGT SFPGGVKDYV DVILSVLPLA SGSIRTVLDI GCGVASFGAF LLNYKILTMS
     IAPRDIHEAQ VQFALERGLP AMLGVLSTYK LPYPSRSFDM VHCSRCLVNW TSYDGLYLME
     VDRVLRPEGY WVLSGPPVAS RVKFKNQKRD SKELQNQMEK LNDVFRRLCW EKIAESYPVV
     IWRKPSNHLQ CRKRLKALKF PGLCSSSDPD AAWYKEMEPC ITPLPDVNDT NKTVLKNWPE
     RLNHVPRMKT GSIQGTTIAG FKADTNLWQR RVLYYDTKFK FLSNGKYRNV IDMNAGLGGF
     AAALIKYPMW VMNVVPFDLK PNTLGVVYDR GLIGTYMNWC EALSTYPRTY DLIHANGVFS
     LYLDKCDIVD ILLEMQRILR PEGAVIIRDR FDVLVKVKAI TNQMRWNGTM YPEDNSVFDH
     GTILIVDNSI K