PMTN_ARATH
ID PMTN_ARATH Reviewed; 589 AA.
AC Q9SIZ3; Q9XEF5;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Probable methyltransferase PMT23;
DE EC=2.1.1.-;
GN OrderedLocusNames=At2g40280; ORFNames=T07M07.16, T3G21.5, T7M7.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10207155;
RA Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.;
RT "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07.";
RL Genome Res. 9:325-333(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=17461780; DOI=10.1111/j.1365-313x.2007.03123.x;
RA Krupkova E., Immerzeel P., Pauly M., Schmulling T.;
RT "The TUMOROUS SHOOT DEVELOPMENT2 gene of Arabidopsis encoding a putative
RT methyltransferase is required for cell adhesion and co-ordinated plant
RT development.";
RL Plant J. 50:735-750(2007).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-
CC pass type II membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; AF085279; AAD25943.1; -; Genomic_DNA.
DR EMBL; AC007020; AAD25663.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC09806.1; -; Genomic_DNA.
DR EMBL; AY059871; AAL24353.1; -; mRNA.
DR EMBL; AY093322; AAM13321.1; -; mRNA.
DR PIR; E84827; E84827.
DR RefSeq; NP_565926.1; NM_129586.3.
DR AlphaFoldDB; Q9SIZ3; -.
DR PaxDb; Q9SIZ3; -.
DR PRIDE; Q9SIZ3; -.
DR ProteomicsDB; 234885; -.
DR EnsemblPlants; AT2G40280.1; AT2G40280.1; AT2G40280.
DR GeneID; 818620; -.
DR Gramene; AT2G40280.1; AT2G40280.1; AT2G40280.
DR KEGG; ath:AT2G40280; -.
DR Araport; AT2G40280; -.
DR TAIR; locus:2063078; AT2G40280.
DR eggNOG; ENOG502QQAS; Eukaryota.
DR HOGENOM; CLU_010485_2_2_1; -.
DR InParanoid; Q9SIZ3; -.
DR OMA; VHMSYLL; -.
DR OrthoDB; 465444at2759; -.
DR PhylomeDB; Q9SIZ3; -.
DR PRO; PR:Q9SIZ3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIZ3; baseline and differential.
DR Genevisible; Q9SIZ3; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0000137; C:Golgi cis cisterna; HDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 2.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10108; PTHR10108; 1.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; SSF53335; 2.
PE 2: Evidence at transcript level;
KW Glycoprotein; Golgi apparatus; Membrane; Methyltransferase;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..589
FT /note="Probable methyltransferase PMT23"
FT /id="PRO_0000393263"
FT TOPO_DOM 1..4
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 5..25
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 26..589
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT CARBOHYD 70
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 375
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 442
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 589 AA; 66773 MW; A7F227D15772E0C2 CRC64;
MAISVQHVVV LLLSTLLIAI TFFLFTSDNA RFPFPSLSTT DYYTPIPKSP IPHRIVDVSS
DQTPQKMKLN TSLEVGELKW DLCKGAESVD YIPCLDNYAA IKQLKSRRHM EHRERHCPEP
SPKCLLPLPD NYKPPVPWPK SRDMIWYDNV PHPKLVEYKK EQNWVKKEGE FLVFPGGGTQ
FKFGVTHYVE FIEKALPSIK WGKNIRVVLD VGCGVASFGG SLLDKDVITM SFAPKDEHEA
QIQFALERGI PATLSVIGTQ QLTFPSNAFD LIHCARCRVH WDADGGKPLL ELNRVLRPGG
FFIWSATPVY RDNDRDSRIW NEMVSLTKSI CWKVVTKTVD SSGIGLVIYQ KPTSESCYNK
RSTQDPPLCD KKEANGSWYV PLAKCLSKLP SGNVQSWPEL WPKRLVSVKP QSISVKAETL
KKDTEKWSAS VSDVYLKHLA VNWSTVRNVM DMNAGFGGFA AALINLPLWV MNVVPVDKPD
TLSVVYDRGL IGVYHDWCES VNTYPRTYDL LHSSFLLGDL TQRCEIVQVV AEIDRIVRPG
GYLVVQDNME TIMKLESILG SLHWSTKIYE DRFLVGRKGF WRPAKPELR
