PNC1_SOYBN
ID PNC1_SOYBN Reviewed; 318 AA.
AC B6ZJZ9;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Peroxisomal adenine nucleotide carrier 1;
DE Short=GmPNC1;
GN Name=PNC1; OrderedLocusNames=Glyma02g11800;
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL
RP STAGE, AND INDUCTION.
RX PubMed=19073762; DOI=10.1105/tpc.108.062877;
RA Arai Y., Hayashi M., Nishimura M.;
RT "Proteomic identification and characterization of a novel peroxisomal
RT adenine nucleotide transporter supplying ATP for fatty acid beta-oxidation
RT in soybean and Arabidopsis.";
RL Plant Cell 20:3227-3240(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82;
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
CC -!- FUNCTION: Peroxisomal adenine nucleotide transporter catalyzing the
CC counterexchange of ATP with AMP. ATP is needed by reactions that
CC generate acyl-CoA for peroxisomal fatty acid beta-oxidation during
CC postgerminative growth. Required for the conversion of seed-reserved
CC triacylglycerols into sucrose that is necessary for growth before the
CC onset of photosynthesis. {ECO:0000269|PubMed:19073762}.
CC -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC {ECO:0000269|PubMed:19073762}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:19073762}.
CC -!- DEVELOPMENTAL STAGE: Increased expression until 5 days after
CC germination and then declines during growth under constant darkness.
CC {ECO:0000269|PubMed:19073762}.
CC -!- INDUCTION: Down-regulated upon illumination in seedlings germinated in
CC the dark. {ECO:0000269|PubMed:19073762}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; AB442083; BAH03204.1; -; mRNA.
DR EMBL; CM000835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001235739.1; NM_001248810.1.
DR AlphaFoldDB; B6ZJZ9; -.
DR SMR; B6ZJZ9; -.
DR STRING; 3847.GLYMA02G11800.1; -.
DR PRIDE; B6ZJZ9; -.
DR EnsemblPlants; KRH70707; KRH70707; GLYMA_02G106100.
DR EnsemblPlants; KRH70708; KRH70708; GLYMA_02G106100.
DR GeneID; 100301879; -.
DR Gramene; KRH70707; KRH70707; GLYMA_02G106100.
DR Gramene; KRH70708; KRH70708; GLYMA_02G106100.
DR KEGG; gmx:100301879; -.
DR eggNOG; KOG0769; Eukaryota.
DR HOGENOM; CLU_015166_6_3_1; -.
DR InParanoid; B6ZJZ9; -.
DR OMA; TELLMMA; -.
DR OrthoDB; 1126848at2759; -.
DR Proteomes; UP000008827; Chromosome 2.
DR Genevisible; B6ZJZ9; GM.
DR GO; GO:0005779; C:integral component of peroxisomal membrane; IBA:GO_Central.
DR GO; GO:0005777; C:peroxisome; IDA:UniProtKB.
DR GO; GO:0015217; F:ADP transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0005347; F:ATP transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0015866; P:ADP transport; IDA:UniProtKB.
DR GO; GO:0015867; P:ATP transport; IDA:UniProtKB.
DR GO; GO:0006635; P:fatty acid beta-oxidation; ISS:UniProtKB.
DR GO; GO:0007031; P:peroxisome organization; IBA:GO_Central.
DR GO; GO:0090351; P:seedling development; ISS:UniProtKB.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR045900; Peroxisomal_Ade_carrier.
DR PANTHER; PTHR46650; PTHR46650; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Antiport; Membrane; Peroxisome; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..318
FT /note="Peroxisomal adenine nucleotide carrier 1"
FT /id="PRO_0000420692"
FT TRANSMEM 8..28
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 5..94
FT /note="Solcar 1"
FT REPEAT 104..184
FT /note="Solcar 2"
FT REPEAT 202..296
FT /note="Solcar 3"
SQ SEQUENCE 318 AA; 34769 MW; 4A2F8642948F3740 CRC64;
MNVDLESLAE ATSGAIGSLI STTILYPLDT CKTKYQAEAR SSGRTKYRNL TDVLLEAISN
RQVLSLYQGL GTKNLQSFIS QFVYFYGYSY FKRLYLEKSG YKSIGTKANL VIAAAAGACT
AIATQPLDTA SSRMQTSEFG KSKGLLKTLT EGNWSDAFDG LSISLLLTSN PAIQYTVFDQ
LKQRALKNKQ DNADKGTSPA SLSAFMAFLL GAISKSIATC LTYPAIRCKV IIQAADSAEE
TSKTKIKSQK TVLSVLYGIW KREGILGYFK GLHAQILKTV LSSALLLMIK EKISASTWVL
ILALKRYLLL PRGKVKNL
