ID   PNG1_ASPOR              Reviewed;         457 AA.
AC   Q2UPS5;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Protein png1;
GN   Name=png1; ORFNames=AO090005001528;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- SIMILARITY: Belongs to the transglutaminase-like superfamily. PNGase
CC       family. {ECO:0000305}.
CC   -!- CAUTION: Although strongly related to the peptide:N-glycanase enzyme,
CC       it lacks the conserved active site Cys in position 259, which is
CC       replaced by a Val residue suggesting that it has no activity.
CC       {ECO:0000305}.
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DR   EMBL; AP007151; BAE56440.1; -; Genomic_DNA.
DR   RefSeq; XP_001818442.1; XM_001818390.2.
DR   AlphaFoldDB; Q2UPS5; -.
DR   SMR; Q2UPS5; -.
DR   STRING; 510516.Q2UPS5; -.
DR   EnsemblFungi; BAE56440; BAE56440; AO090005001528.
DR   GeneID; 5990387; -.
DR   KEGG; aor:AO090005001528; -.
DR   VEuPathDB; FungiDB:AO090005001528; -.
DR   HOGENOM; CLU_031058_1_0_1; -.
DR   OMA; WIHVDAC; -.
DR   Proteomes; UP000006564; Chromosome 1.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProt.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   Pfam; PF03835; Rad4; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..457
FT                   /note="Protein png1"
FT                   /id="PRO_0000248985"
FT   REGION          30..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..89
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..104
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..424
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         201
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         204
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         233
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         238
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   457 AA;  52116 MW;  EC90B0B653B9FE9B CRC64;
     MADSIHHSQR AQGSNNFDVS ELTNAFEQLM RNKRFHRLQE HSRARTHSPS PSPSQVSSPG
     PYAPPHPSRA PPPPPTAAPF QPPQYPQQPQ QYPSNQSSML QGLPIVPSPP QDQASLKFRN
     LLHVLSVTPT KYENPGLLDE ALSLIPLDRL YSEAEEESQI LQAQAASVGG RPEWGYQDCV
     IRSLLRWFKG SFFQFVNNPP CSRCFRPTIA QGNTPPLPDE TARGATRVEL YRCSEMSCGA
     YERFPRYSDV WQLLQSRRGR VGEWANCFSM FCRALGGRVR WVWNSEDYVW TEIYSEHQRR
     WVHVDACEGA WDQPRLYAEG WGRKMSYCIA FSIDGATDVT RRYVRSSAKH GAARNRAPEE
     VVHWVILEIR RKRRENLSKT DQKRLMKEDE REEKELRHYT ASALAAELNN LLPQNQTTGR
     LDEQKTPVSR QEAAAEWLAA SQRNSGHSGP DHSQGGR