PNM8A_MOUSE
ID PNM8A_MOUSE Reviewed; 430 AA.
AC Q80VM8; Q8C533;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Paraneoplastic antigen-like protein 8A;
DE AltName: Full=PNMA-like protein 1;
GN Name=Pnma8a; Synonyms=Pnmal1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-246.
RC STRAIN=C57BL/6J; TISSUE=Spinal cord;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SIMILARITY: Belongs to the PNMA family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC048228; AAH48228.1; -; mRNA.
DR EMBL; AK079661; BAC37719.1; -; mRNA.
DR CCDS; CCDS20858.1; -.
DR RefSeq; NP_001007570.1; NM_001007569.1.
DR RefSeq; XP_006540424.1; XM_006540361.3.
DR AlphaFoldDB; Q80VM8; -.
DR STRING; 10090.ENSMUSP00000040929; -.
DR iPTMnet; Q80VM8; -.
DR PhosphoSitePlus; Q80VM8; -.
DR PaxDb; Q80VM8; -.
DR PeptideAtlas; Q80VM8; -.
DR PRIDE; Q80VM8; -.
DR ProteomicsDB; 289845; -.
DR Antibodypedia; 2037; 56 antibodies from 20 providers.
DR Ensembl; ENSMUST00000038163; ENSMUSP00000040929; ENSMUSG00000041141.
DR GeneID; 71691; -.
DR KEGG; mmu:71691; -.
DR UCSC; uc009fip.1; mouse.
DR CTD; 55228; -.
DR MGI; MGI:1918941; Pnmal1.
DR VEuPathDB; HostDB:ENSMUSG00000041141; -.
DR eggNOG; ENOG502TEDX; Eukaryota.
DR GeneTree; ENSGT01030000234522; -.
DR HOGENOM; CLU_050538_0_0_1; -.
DR InParanoid; Q80VM8; -.
DR OMA; WEDVVHL; -.
DR OrthoDB; 820525at2759; -.
DR PhylomeDB; Q80VM8; -.
DR TreeFam; TF335054; -.
DR BioGRID-ORCS; 71691; 2 hits in 71 CRISPR screens.
DR ChiTaRS; Pnmal1; mouse.
DR PRO; PR:Q80VM8; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q80VM8; protein.
DR Bgee; ENSMUSG00000041141; Expressed in CA1 field of hippocampus and 208 other tissues.
DR Genevisible; Q80VM8; MM.
DR InterPro; IPR026523; PNMA.
DR PANTHER; PTHR23095; PTHR23095; 1.
DR Pfam; PF14893; PNMA; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..430
FT /note="Paraneoplastic antigen-like protein 8A"
FT /id="PRO_0000325838"
FT REGION 219..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..250
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 48062 MW; BA5722230F40CA77 CRC64;
MSEPVAMTLL EDWCRGMGMD IHRSLLVTGI PEYCSHAEIE ETLNGVLLPL GTYRVLNKIF
LRQENVKAAL VEVSEGVNLS SIPREFPGRG GVWRVVCRDP TQDDDFLKNL NEFLDGEGRT
WEDMVRLLKL NPNPPLPNSN QPPPNWAEAL GLLLGAVVQV IFYMDAAIRS RDEEARAEEA
AEAELMEAWA STARKRVKKE PGLGVEVGSA FKMEDRNYWK NTEDHGDPPK PLVRRPGGKI
RSRRRKQKKN LKQEPICWRK SQGSNYNSNY NKVNLEAGEA AQSSEIPESV KSNKKPFVKQ
EETVWKKKRV WRDPSDLPRS ALPAADSPGN LEDSDQDGGP ENPAKKKAMT WASNKIPVPT
RKKKKMVSLG TLSYVLLDAE ATKNKTAILK KGLGARRAVS VPHDAPASTS RPQKTKLGAF
PRVSKDSRKL
