PNMA1_RAT
ID PNMA1_RAT Reviewed; 353 AA.
AC Q8VHZ4; Q4V8N4;
DT 24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Paraneoplastic antigen Ma1 homolog;
GN Name=Pnma1; Synonyms=Ma1;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX PubMed=10050892; DOI=10.1093/brain/122.1.27;
RA Dalmau J., Gultekin S.H., Voltz R., Hoard R., DesChamps T., Balmaceda C.,
RA Batchelor T., Gerstner E., Eichen J., Frennier J., Posner J.B.,
RA Rosenfeld M.R.;
RT "Ma1, a novel neuron- and testis-specific protein, is recognized by the
RT serum of patients with paraneoplastic neurological disorders.";
RL Brain 122:27-39(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Testis and brain specific.
CC {ECO:0000269|PubMed:10050892}.
CC -!- SIMILARITY: Belongs to the PNMA family. {ECO:0000305}.
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DR EMBL; AF335505; AAL73196.1; -; mRNA.
DR EMBL; BC097291; AAH97291.1; -; mRNA.
DR RefSeq; NP_570833.1; NM_130820.2.
DR AlphaFoldDB; Q8VHZ4; -.
DR SMR; Q8VHZ4; -.
DR STRING; 10116.ENSRNOP00000014018; -.
DR PaxDb; Q8VHZ4; -.
DR Ensembl; ENSRNOT00000014018; ENSRNOP00000014018; ENSRNOG00000010553.
DR GeneID; 170636; -.
DR KEGG; rno:170636; -.
DR UCSC; RGD:621230; rat.
DR CTD; 9240; -.
DR RGD; 621230; Pnma1.
DR eggNOG; ENOG502SPHT; Eukaryota.
DR GeneTree; ENSGT01030000234522; -.
DR HOGENOM; CLU_014694_0_0_1; -.
DR InParanoid; Q8VHZ4; -.
DR OMA; EHTNEVM; -.
DR OrthoDB; 820525at2759; -.
DR PhylomeDB; Q8VHZ4; -.
DR TreeFam; TF335054; -.
DR PRO; PR:Q8VHZ4; -.
DR Proteomes; UP000002494; Chromosome 6.
DR Bgee; ENSRNOG00000010553; Expressed in testis and 13 other tissues.
DR Genevisible; Q8VHZ4; RN.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0002437; P:inflammatory response to antigenic stimulus; IDA:UniProtKB.
DR InterPro; IPR026523; PNMA.
DR InterPro; IPR026528; PNMA1.
DR PANTHER; PTHR23095; PTHR23095; 1.
DR PANTHER; PTHR23095:SF17; PTHR23095:SF17; 1.
DR Pfam; PF14893; PNMA; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..353
FT /note="Paraneoplastic antigen Ma1 homolog"
FT /id="PRO_0000155201"
SQ SEQUENCE 353 AA; 39793 MW; FFC3A717FDCEADA3 CRC64;
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DETEIEETLQ AAMPQVSYRV LGRMFWREEN
AKAALLELTG TVDYSLIPRE MPGKGGLWKV VFKPPTSDAE FLERLHLFLA REGWTVQDVA
RVLGFQNPAP APGPEMPAEM LNYILDNVIQ PLVESIWYKK LTLFSGRDIP GPGEETFDSW
LEHSNEVIEE WQVSDIEKRR RLMESLRGPA ADVIRILKTN NPAITTAECL KALEQVFGSV
ESSRDAQVRF LNTYQNPGEK LSSYVIRLEP LLQKVVDKGA IDKDNVNQAR LEQVIAGANH
SGALRRQLWL TGATEGPAPN LFQLLVQIRE EEAKEEEEEA EAALLQLGLE GHF