ID   PNO1_ASPOR              Reviewed;         260 AA.
AC   Q2UMG1;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Pre-rRNA-processing protein pno1;
GN   Name=pno1; ORFNames=AO090003000014;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Required for small ribosomal subunit (SSU) synthesis. Has a
CC       role in the processing of early nucleolar and late cytoplasmic pre-RNA
CC       species (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the small ribosomal subunit, ribosomal RNA
CC       processing complex (SSU RRP complex). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99216}.
CC       Nucleus, nucleolus {ECO:0000250|UniProtKB:Q99216}.
CC   -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP007155; BAE57254.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2UMG1; -.
DR   SMR; Q2UMG1; -.
DR   STRING; 510516.Q2UMG1; -.
DR   EnsemblFungi; BAE57254; BAE57254; AO090003000014.
DR   HOGENOM; CLU_064992_0_2_1; -.
DR   OMA; IHIMGSF; -.
DR   Proteomes; UP000006564; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:EnsemblFungi.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0043248; P:proteasome assembly; IEA:EnsemblFungi.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR039912; PNO1-like.
DR   PANTHER; PTHR12826:SF13; PTHR12826:SF13; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding.
FT   CHAIN           1..260
FT                   /note="Pre-rRNA-processing protein pno1"
FT                   /id="PRO_0000278364"
FT   DOMAIN          181..233
FT                   /note="KH"
SQ   SEQUENCE   260 AA;  28728 MW;  097E7E769D67E764 CRC64;
     MPAPTALKGL DQTTTAGVPV TQAAIVQDDE VLIDAQTSAE ESVPVLAPLG ENAQDTDMRI
     DEEGRPVFTP AKDTNTVYRV ETRKVPVPPH RFSPLKASWS RIYPPLVEHL KLQVRMNIKS
     RAVELRTSKF TTDTGALQKG EDFVKAFTLG FDVDDAIALL RLDDLYIRSF EIRDVKASLH
     GEHLSRAIGR IAGKDGKLKH SIENATRTRI VLADQKIHLL GGYRNILVAQ EAVVSLILGS
     PPGKVYGNLR KVASRMKERF