PNO1_CAEEL
ID PNO1_CAEEL Reviewed; 277 AA.
AC O18216;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=RNA-binding protein pno-1;
GN Name=pno-1 {ECO:0000312|WormBase:Y53C12B.2};
GN ORFNames=Y53C12B.2 {ECO:0000312|WormBase:Y53C12B.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
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DR EMBL; Z99278; CAB16491.1; -; Genomic_DNA.
DR PIR; T27134; T27134.
DR RefSeq; NP_496099.1; NM_063698.4.
DR AlphaFoldDB; O18216; -.
DR SMR; O18216; -.
DR BioGRID; 39856; 2.
DR STRING; 6239.Y53C12B.2; -.
DR EPD; O18216; -.
DR PaxDb; O18216; -.
DR PeptideAtlas; O18216; -.
DR EnsemblMetazoa; Y53C12B.2.1; Y53C12B.2.1; WBGene00013144.
DR GeneID; 174534; -.
DR KEGG; cel:CELE_Y53C12B.2; -.
DR UCSC; Y53C12B.2; c. elegans.
DR CTD; 174534; -.
DR WormBase; Y53C12B.2; CE14896; WBGene00013144; pno-1.
DR eggNOG; KOG3273; Eukaryota.
DR GeneTree; ENSGT00390000018052; -.
DR HOGENOM; CLU_064992_2_1_1; -.
DR InParanoid; O18216; -.
DR OMA; IHIMGSF; -.
DR OrthoDB; 1269649at2759; -.
DR PhylomeDB; O18216; -.
DR PRO; PR:O18216; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00013144; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1370.10; -; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR039912; PNO1-like.
DR PANTHER; PTHR12826:SF13; PTHR12826:SF13; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; SSF54791; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..277
FT /note="RNA-binding protein pno-1"
FT /id="PRO_0000270549"
FT DOMAIN 198..250
FT /note="KH"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 30707 MW; 4850A83FE7F4439C CRC64;
MATSSSAFDD ELPMEEGMPE LLDDEDVPST LPSLLEQNLD TAPKGDEFKL VKRKRKSGNA
IDVVMEDVSQ VDEDATADTA DDSTGPKSSK RTKGVKGESR VVPVPKHRYT PLKDNWVNIF
TPIVKNLGLQ VRFNLKKRQV EIRNPVDRED TTDLQKATDF VRAFILGFEV NDAIALIRLD
HLFLETFEVA DVKHSLKGDH VSRAIGRIAG KDGRTKLVIE NTTKTRIVVA NTKIHILGAY
QNLKLARNAV CSLILGSNPS KVYGSLRNMA SRGAERL