ID   PNO1_CHICK              Reviewed;         242 AA.
AC   Q5F414;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=RNA-binding protein PNO1;
GN   Name=PNO1; ORFNames=RCJMB04_3n12;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Positively regulates dimethylation of two adjacent adenosines
CC       in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
CC       {ECO:0000250|UniProtKB:Q9NRX1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9NRX1}.
CC   -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
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DR   EMBL; AJ851486; CAH65120.1; -; mRNA.
DR   RefSeq; NP_001072958.1; NM_001079490.1.
DR   AlphaFoldDB; Q5F414; -.
DR   SMR; Q5F414; -.
DR   STRING; 9031.ENSGALP00000014788; -.
DR   PaxDb; Q5F414; -.
DR   Ensembl; ENSGALT00000014804; ENSGALP00000014788; ENSGALG00000009093.
DR   GeneID; 769547; -.
DR   KEGG; gga:769547; -.
DR   CTD; 56902; -.
DR   VEuPathDB; HostDB:geneid_769547; -.
DR   eggNOG; KOG3273; Eukaryota.
DR   GeneTree; ENSGT00390000018052; -.
DR   HOGENOM; CLU_064992_2_0_1; -.
DR   InParanoid; Q5F414; -.
DR   OMA; IHIMGSF; -.
DR   OrthoDB; 1269649at2759; -.
DR   PhylomeDB; Q5F414; -.
DR   PRO; PR:Q5F414; -.
DR   Proteomes; UP000000539; Chromosome 3.
DR   Bgee; ENSGALG00000009093; Expressed in muscle tissue and 14 other tissues.
DR   ExpressionAtlas; Q5F414; baseline and differential.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1370.10; -; 2.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR039912; PNO1-like.
DR   PANTHER; PTHR12826:SF13; PTHR12826:SF13; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..242
FT                   /note="RNA-binding protein PNO1"
FT                   /id="PRO_0000270543"
FT   DOMAIN          158..215
FT                   /note="KH"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   242 AA;  26426 MW;  473AEDA823D8DD29 CRC64;
     METEAADESG FTSVASKRGR RKRRAAGAEP MEAAESAEAA GPQPSKRPAF PPLPAAALGV
     GKGEVRKVPV PANRYTPLKE NWMKIFTPIV EHLQLQIRFN LKTRNVEIKT CSETKDLSAL
     TKAADFVKAF ILGFQVEDAL ALIRLDDLFL ESFEVTDVKP LKGDHLSRAI GRIAGKGGKT
     KFTIENVTRT RIVLADSKIH ILGSFQNIKM ARTAICNLIL GSPPSKVYGN IRAVASRAAE
     RF