ID   PNO1_ORYLA              Reviewed;         243 AA.
AC   Q6VBQ6;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=RNA-binding protein PNO1;
GN   Name=pno1;
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15497447; DOI=10.1080/10425170410001702159;
RA   Zhou G.-J., Zhang Y., Wang J., Guo J.H., Ni J., Zhong Z.-M., Wang L.-Q.,
RA   Dang Y.-J., Dai J.F., Yu L.;
RT   "Cloning and characterization of a novel human RNA binding protein gene
RT   PNO1.";
RL   DNA Seq. 15:219-224(2004).
CC   -!- FUNCTION: Positively regulates dimethylation of two adjacent adenosines
CC       in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
CC       {ECO:0000250|UniProtKB:Q9NRX1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9NRX1}.
CC   -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY344059; AAQ24836.1; -; mRNA.
DR   RefSeq; NP_001098253.1; NM_001104783.2.
DR   AlphaFoldDB; Q6VBQ6; -.
DR   SMR; Q6VBQ6; -.
DR   STRING; 8090.ENSORLP00000002947; -.
DR   GeneID; 100049395; -.
DR   KEGG; ola:100049395; -.
DR   CTD; 56902; -.
DR   eggNOG; KOG3273; Eukaryota.
DR   InParanoid; Q6VBQ6; -.
DR   OrthoDB; 1269649at2759; -.
DR   Proteomes; UP000001038; Unplaced.
DR   Proteomes; UP000265180; Chromosome 9.
DR   Proteomes; UP000265200; Chromosome 9.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1370.10; -; 2.
DR   InterPro; IPR041174; KH_8.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR039912; PNO1-like.
DR   PANTHER; PTHR12826:SF13; PTHR12826:SF13; 1.
DR   Pfam; PF17903; KH_8; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..243
FT                   /note="RNA-binding protein PNO1"
FT                   /id="PRO_0000270545"
FT   DOMAIN          164..216
FT                   /note="KH"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   243 AA;  27125 MW;  A5BEDFE2DF96D315 CRC64;
     MDASENGATA PEKHDDGESF TKVKSKKSQK RKLEPDGGIT MEVEQPNKRP HFPPISADKL
     RGPDEMRKVA VPAHRYTPLK ENWLKIFTPI VENLQLQVRF NLKTRNVEIK TCKETQDIAA
     LTKAADFIKA FVLGFQVDDA MALIRLDELF LESFDVTDVK PLKGDHLSRA IGRIAGKGGK
     TKFTIENVTK TRIVLADTKI HILGSFQNIK MARTAICNLI LGSPPSKVYG NIRAVASRTA
     ERF