PNO1_YARLI
ID PNO1_YARLI Reviewed; 258 AA.
AC Q6C7G0;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Pre-rRNA-processing protein PNO1;
GN Name=PNO1; OrderedLocusNames=YALI0E01122g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Required for small ribosomal subunit (SSU) synthesis. Has a
CC role in the processing of early nucleolar and late cytoplasmic pre-RNA
CC species (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the small ribosomal subunit, ribosomal RNA
CC processing complex (SSU RRP complex). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99216}.
CC Nucleus, nucleolus {ECO:0000250|UniProtKB:Q99216}.
CC -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
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DR EMBL; CR382131; CAG78981.1; -; Genomic_DNA.
DR RefSeq; XP_503402.1; XM_503402.1.
DR AlphaFoldDB; Q6C7G0; -.
DR SMR; Q6C7G0; -.
DR STRING; 4952.CAG78981; -.
DR EnsemblFungi; CAG78981; CAG78981; YALI0_E01122g.
DR GeneID; 2912939; -.
DR KEGG; yli:YALI0E01122g; -.
DR VEuPathDB; FungiDB:YALI0_E01122g; -.
DR HOGENOM; CLU_064992_0_2_1; -.
DR InParanoid; Q6C7G0; -.
DR OMA; IHIMGSF; -.
DR Proteomes; UP000001300; Chromosome E.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1370.10; -; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR039912; PNO1-like.
DR PANTHER; PTHR12826:SF13; PTHR12826:SF13; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; SSF54791; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding.
FT CHAIN 1..258
FT /note="Pre-rRNA-processing protein PNO1"
FT /id="PRO_0000278361"
FT DOMAIN 179..231
FT /note="KH"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 258 AA; 28494 MW; D662783084C64855 CRC64;
MGAPTAKRQT QATEPTTDAP VAIPQTEGAE EDEVMISMDG PREDIAVLQE KDDDAEMTLD
QDGKPRFASA VNAGEGVKPG RMKVPIPPHR MAPLKNEWMK IYPPLVEQLK LQVRMNPRKK
QLELRTCSNT VDNSALQKGT DFVRAFTLGF DVDDAMAIIR LDELYVETFE IKDVKTLQGD
HLGRAIGRIA GKDGKTKFAI ENASRTRVVL ADSKIHILGG FTNIKIAREA IVSLILGSPP
GKVYGNLRIV ASRMKERF