ID   AT1B1_ARTSF             Reviewed;         315 AA.
AC   P25169;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta;
DE   AltName: Full=Sodium/potassium-dependent ATPase beta subunit;
OS   Artemia franciscana (Brine shrimp) (Artemia sanfranciscana).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC   Anostraca; Artemiidae; Artemia.
OX   NCBI_TaxID=6661;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2167242; DOI=10.1016/0014-5793(90)81162-h;
RA   Bhattacharyya K.K., Bergstroem E.E., Hokin L.E.;
RT   "Molecular cloning of the beta-subunit of the Na,K-ATPase in the brine
RT   shrimp, Artemia. The cDNA-derived amino acid sequence shows low homology
RT   with the beta-subunits of vertebrates except in the single transmembrane
RT   and the carboxy-terminal domains.";
RL   FEBS Lett. 269:233-238(1990).
CC   -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC       which catalyzes the hydrolysis of ATP coupled with the exchange of
CC       Na(+) and K(+) ions across the plasma membrane. The beta subunit
CC       regulates, through assembly of alpha/beta heterodimers, the number of
CC       sodium pumps transported to the plasma membrane.
CC   -!- SUBUNIT: The sodium/potassium-transporting ATPase is composed of a
CC       catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an
CC       additional regulatory subunit. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type II
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; X55780; CAA39301.1; -; mRNA.
DR   AlphaFoldDB; P25169; -.
DR   SMR; P25169; -.
DR   GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1660; -; 1.
DR   InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR   InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR   PANTHER; PTHR11523; PTHR11523; 1.
DR   Pfam; PF00287; Na_K-ATPase; 1.
DR   PROSITE; PS00390; ATPASE_NA_K_BETA_1; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; Glycoprotein; Ion transport; Membrane;
KW   Potassium; Potassium transport; Signal-anchor; Sodium; Sodium transport;
KW   Sodium/potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..315
FT                   /note="Sodium/potassium-transporting ATPase subunit beta"
FT                   /id="PRO_0000219113"
FT   TOPO_DOM        1..47
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        69..315
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        198
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        222
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        296
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        145..157
FT                   /evidence="ECO:0000250"
FT   DISULFID        168..182
FT                   /evidence="ECO:0000250"
FT   DISULFID        233..290
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   315 AA;  35955 MW;  787BAA38F99566E8 CRC64;
     MADKKPDEQF VGSGPKETKW QSFKGFVWNS ETSQFMGRTA GSWAKITIFY VIFYTLLAGF
     FAGMLMIFYQ TLDFKIPKWQ NKDSLIGANP GLGFRPMPPE AQVDSTLIQF KHGIKGDWQY
     WVHSLTEFLE PYETLTSSGQ EFTNCDFDKP PQEGKACNFN VELLGDHCTK ENNFGYELGK
     PCVLIKLTDF GWRPEVYNSS AEVPEDMPAD LKSYIKDIET GNKTHMNMVW LSCEGETAND
     KEKIGTITYT PFRGFPAYYY PYLNVPGYLT PVVALQFGSL QNGQAVNVEC KAWANNISRD
     RQRRLGSVHF EIRMD