PNX78_SCOMU
ID PNX78_SCOMU Reviewed; 114 AA.
AC I6S3A9;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 25-MAY-2022, entry version 16.
DE RecName: Full=Putative neurotoxin 7 {ECO:0000303|PubMed:22595790};
DE AltName: Full=Putative neurotoxin 8 {ECO:0000312|EMBL:AFM55027.1};
DE Flags: Precursor;
OS Scolopendra mutilans (Chinese red-headed centipede) (Scolopendra
OS subspinipes mutilans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Scolopendromorpha; Scolopendridae; Scolopendra.
OX NCBI_TaxID=2836329;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT PUTATIVE NEUROTOXIN 8 ARG-101.
RC TISSUE=Venom gland;
RX PubMed=22595790; DOI=10.1074/mcp.m112.018853;
RA Yang S., Liu Z., Xiao Y., Li Y., Rong M., Liang S., Zhang Z., Yu H.,
RA King G.F., Lai R.;
RT "Chemical punch packed in venoms makes centipedes excellent predators.";
RL Mol. Cell. Proteomics 11:640-650(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:22595790}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:22595790}.
CC -!- PTM: Contains 3 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the scolopendra neurotoxin 8 family.
CC {ECO:0000305}.
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DR EMBL; JQ757080; AFM55027.1; -; mRNA.
DR AlphaFoldDB; I6S3A9; -.
DR SMR; I6S3A9; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Disulfide bond; Neurotoxin; Secreted; Signal; Toxin.
FT SIGNAL 1..?
FT /evidence="ECO:0000255"
FT CHAIN ?..114
FT /note="Putative neurotoxin 7"
FT /evidence="ECO:0000305"
FT /id="PRO_0000425495"
FT VARIANT 101
FT /note="P -> R (in putative neurotoxin 8)"
FT /evidence="ECO:0000269|PubMed:22595790"
SQ SEQUENCE 114 AA; 13021 MW; 44B4F5CFFD9D068D CRC64;
MGIRPTLQTN PLVDLLISTS QTQLQNAGLP FPPRSFGCLL VRHSPGCLPG SLWNLPRSRL
PSCLPICLPR CRCWLNRERW RKGDDVFSDF CTKFVSTLIG PTSFAFRFVE FFYL