ID   POA1_CHAGB              Reviewed;         185 AA.
AC   Q2GV19;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=ADP-ribose 1''-phosphate phosphatase;
DE            EC=3.1.3.84;
GN   Name=POA1; ORFNames=CHGG_08185;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: Highly specific phosphatase involved in the metabolism of
CC       ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of
CC       tRNA splicing. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ADP-beta-D-ribose 1''-phosphate + H2O = ADP-D-ribose +
CC         phosphate; Xref=Rhea:RHEA:25029, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:57967, ChEBI:CHEBI:58753; EC=3.1.3.84;
CC   -!- SIMILARITY: Belongs to the POA1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAQ86932.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CH408033; EAQ86932.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_001225841.1; XM_001225840.1.
DR   AlphaFoldDB; Q2GV19; -.
DR   SMR; Q2GV19; -.
DR   STRING; 306901.Q2GV19; -.
DR   EnsemblFungi; EAQ86932; EAQ86932; CHGG_08185.
DR   GeneID; 4393346; -.
DR   eggNOG; ENOG502S60W; Eukaryota.
DR   HOGENOM; CLU_054419_0_0_1; -.
DR   InParanoid; Q2GV19; -.
DR   OrthoDB; 1416296at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.220.10; -; 1.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..185
FT                   /note="ADP-ribose 1''-phosphate phosphatase"
FT                   /id="PRO_0000324906"
FT   DOMAIN          1..185
FT                   /note="Macro"
FT   BINDING         13..15
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         27..29
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         34..39
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         142..148
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   185 AA;  19900 MW;  FB7C6A7A6E47F114 CRC64;
     MSPARLRITD RTGDLFAAPA NTLLIHACNT VGSWGGGIAL AFRNLYPAEF RVYRAHCARS
     TPNQLVGTAL LIAPQRASLN GSGGGGHYIG CLFTSRRFGA ARDPPDRILR ATGPAMRHLM
     RLVAEEEERT GVRIGEVRMC RINAGLFAVP WESSKRALEA MELGDGEVPG CAQGGVVEVV
     AWERA